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The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer.

作者信息

Wang Jiyan, He Tao, Gao Qingle, Chang Hongkai, Dai Xintong, Yang Juze, Liu Shuangping, Zhang Shuai, Shan Changliang, Zhang Chunze

机构信息

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.

Departments of Pathology, Characteristic Medical Center of The Chinese People's Armed Police Force, Tianjin 300162, China.

出版信息

Genes Dis. 2023 Apr 28;11(2):542-545. doi: 10.1016/j.gendis.2023.03.026. eCollection 2024 Mar.

DOI:10.1016/j.gendis.2023.03.026
PMID:37692497
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10491908/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f5e/10491908/0e0d9f5b9266/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f5e/10491908/0e0d9f5b9266/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f5e/10491908/0e0d9f5b9266/gr1.jpg

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Sci Adv. 2022 Apr 29;8(17):eabm3108. doi: 10.1126/sciadv.abm3108.
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