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重症新型冠状病毒肺炎患者俯卧位通气管理方案的构建与应用

Construction and application of prone position ventilation management scheme for severe COVID-19 patients.

作者信息

Chen Xiuwen, Peng Cao, Xiao Yao, Liu Shiqing

机构信息

Teaching and Research Section of Clinical Nursing, Xiangya Hospital, Central South University, Changsha, China.

Department of Operating Room, Xiangya Hospital, Central South University, Changsha, China.

出版信息

Front Physiol. 2023 Aug 24;14:1152723. doi: 10.3389/fphys.2023.1152723. eCollection 2023.

Abstract

Prone position ventilation (PPV) can significantly improve oxygenation index and blood oxygen saturation in most (70%-80%) patients with acute respiratory distress syndrome. However, although PPV is not an invasive procedure, there are many potential PPV-related complications, such as nerve compression, crush injury, venous stasis (e.g., facial oedema), pressure sores, retinal damage, vomiting, and arrhythmia, with an incidence of up to 56.9%. Nursing managers have focused on reducing the occurrence of PPV-related complications and improving safety. To construct a prone ventilation management scheme for patients with severe coronavirus disease 2019 (COVID-19) and analyse its application effect. Based on a previous evidence-based study combined with the COVID-19 Diagnosis and Treatment Protocol (Trial Edition 9), a prone ventilation management protocol for severe COVID-19 was formulated and applied to COVID-19 patients in the intensive care unit of a designated hospital. A prospective self-control study was used to compare changes in the oxygenation index and other outcome indicators before and after the intervention. The oxygenation index of patients after intervention (321.22 ± 19.77 mmHg) was significantly higher ( < 0.05) than before intervention (151.59 ± 35.49 mmHg). The difference in oxygenation index in different prone position ventilation durations was statistically significant ( < 0.05). Nursing quality evaluation indicators showed that the implementation rate of gastric residual volume assessment was 100% and the incidence of occupational exposure and cross-infection was 0%; the incidences of pressure ulcers, drug extravasation, and facial oedema were 13.64% (3/22), 4.54% (1/22), and 4.54% (1/22), respectively. The incidence of unplanned extubation, aspiration, and falls/falls was 0%.

摘要

俯卧位通气(PPV)可显著改善大多数(70%-80%)急性呼吸窘迫综合征患者的氧合指数和血氧饱和度。然而,尽管PPV并非侵入性操作,但仍存在许多与PPV相关的潜在并发症,如神经受压、挤压伤、静脉淤血(如面部水肿)、压疮、视网膜损伤、呕吐和心律失常,发生率高达56.9%。护理管理者一直致力于减少与PPV相关并发症的发生并提高安全性。为构建2019冠状病毒病(COVID-19)重症患者的俯卧位通气管理方案并分析其应用效果。基于既往循证研究并结合《新型冠状病毒肺炎诊疗方案(试行第九版)》,制定了重症COVID-19俯卧位通气管理方案,并应用于某定点医院重症监护病房的COVID-19患者。采用前瞻性自身对照研究比较干预前后氧合指数及其他结局指标的变化。干预后患者的氧合指数(321.22±19.77mmHg)显著高于干预前(151.59±35.49mmHg)(<0.05)。不同俯卧位通气时长的氧合指数差异具有统计学意义(<0.05)。护理质量评价指标显示,胃残余量评估执行率为100%,职业暴露和交叉感染发生率为0%;压疮、药物外渗和面部水肿的发生率分别为13.64%(3/22)、4.54%(1/22)和4.54%(1/22)。非计划性拔管、误吸和跌倒/坠床的发生率为0%。

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