Al Jarallah Othman Jarallah, Alsakran Wael A, Galvez Alberto
Department of Surgery, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Department of ophthalmology, King Khalid Eye Specialist Hospital, Riyadh, Saudi Arabia.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1075-S1078. doi: 10.4103/jpbs.jpbs_215_23. Epub 2023 Jul 11.
To provide the demographic data, risk factors, and visual prognosis of patients from a Saudi population diagnosed with non-arteritic anterior ischemic optic neuropathy (NAION).
A retrospective observational case series of 120 patients (146 eyes) with NAION from the King Khaled Eye Specialist Hospital or King Abdulaziz University Hospital from 1998 to 2015. Patients with other retinal pathology or glaucoma were excluded from the study. Additionally, a subgroup analysis was performed to compare the long-term assessment between diabetic and non-diabetic patients and its effects on NAION.
The mean duration of follow-up was 1.7 ± 2.4 years. The mean age of the study population was 55.0 ± 10.1 years. NAION was present in the fellow eye of 26 patients, and the median time for involvement was less than 1 year from the presentation. There was no significant difference in the best-corrected visual acuity between diabetics and non-diabetics at presentation or last visit ( = 0.868, = 0.599, respectively).
The majority of patients with NAION also had coexisting diabetes mellitus. Diabetes mellitus had no significant effect on NAION during the presentation, follow-up, and last visit.
提供沙特人群中被诊断为非动脉炎性前部缺血性视神经病变(NAION)患者的人口统计学数据、危险因素及视力预后情况。
这是一项回顾性观察病例系列研究,纳入了1998年至2015年期间在沙特国王哈立德眼科专科医院或阿卜杜勒阿齐兹国王大学医院就诊的120例(146只眼)NAION患者。研究排除了患有其他视网膜病变或青光眼的患者。此外,还进行了亚组分析,以比较糖尿病患者和非糖尿病患者的长期评估情况及其对NAION的影响。
平均随访时间为1.7±2.4年。研究人群的平均年龄为55.0±10.1岁。26例患者的对侧眼也出现了NAION,受累的中位时间距首次就诊不到1年。糖尿病患者和非糖尿病患者在初次就诊或最后一次就诊时的最佳矫正视力无显著差异(分别为=0.868,=0.599)。
大多数NAION患者同时患有糖尿病。糖尿病在初次就诊、随访及最后一次就诊期间对NAION无显著影响。