Dixit Arti, Parekh Nirav Hemant, Anand Rakesh, Kamal Nitesh, Badiyani Bhumika K, Kumar Amit, Obulareddy Vishnu Teja
Department of Public Health Dentistry, Vaidik Dental College and Research Centre, Daman (U.T.) India.
DDS MHA BDS, Owner and CEO of Smile Rite Dental Care, Connecticut USA, Graduated from NYU College of Dentistry, United States.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S977-S980. doi: 10.4103/jpbs.jpbs_260_23. Epub 2023 Jul 11.
The purpose of this study was to determine which factors contribute to the development of oral precancerous lesions and subsequent mouth cancer.
Throughout the trial, 450 patients agreed to participate in the investigation. The subjects comprised patients with squamous cell carcinoma ( = 79), oral submucous fibrosis (OSF) ( = 200), leukoplakia ( = 41), lichen planus ( = 10), and controls ( = 120). Statistical analysis of the data was carried out using the Chi-square and regression analysis.
All oral precancerous lesions were shown to have a high prevalence of chewing, which was found to have a strong link with oral cancer. Oral precancerous lesions and cancer were also substantially connected with the length of time someone had the habit and how often they engaged in it.
Oral cancer and precancerous lesions were determined to be less of a worry when other risks such as drinking and smoking were taken into account.
本研究的目的是确定哪些因素会导致口腔癌前病变及随后的口腔癌的发生。
在整个试验过程中,450名患者同意参与调查。受试者包括鳞状细胞癌患者(n = 79)、口腔黏膜下纤维化(OSF)患者(n = 200)、白斑患者(n = 41)、扁平苔藓患者(n = 10)以及对照组(n = 120)。使用卡方检验和回归分析对数据进行统计分析。
所有口腔癌前病变均显示咀嚼的发生率很高,且发现咀嚼与口腔癌有密切联系。口腔癌前病变和癌症也与某人有该习惯的时间长短以及他们进行咀嚼的频率密切相关。
当考虑到饮酒和吸烟等其他风险时,口腔癌和癌前病变被认为不那么令人担忧。