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热带假丝酵母的当前进展:酵母概述及生物技术应用

Current advances in Candida tropicalis: Yeast overview and biotechnological applications.

作者信息

Queiroz Sarah de Souza, Jofre Fanny Machado, Bianchini Italo de Andrade, Boaes Tatiane da Silva, Bordini Fernanda Weber, Chandel Anuj Kumar, Felipe Maria das Graças de Almeida

机构信息

Department of Biotechnology, Engineering School of Lorena, Universidade de São Paulo, São Paulo, Brazil.

出版信息

Biotechnol Appl Biochem. 2023 Dec;70(6):2069-2087. doi: 10.1002/bab.2510. Epub 2023 Sep 11.

DOI:10.1002/bab.2510
PMID:37694532
Abstract

Candida tropicalis is a nonconventional yeast with medical and industrial significance, belonging to the CTG clade. Recent advancements in whole-genome sequencing and genetic analysis revealed its close relation to other unconventional yeasts of biotechnological importance. C. tropicalis is known for its immense potential in synthesizing various valuable biomolecules such as ethanol, xylitol, biosurfactants, lipids, enzymes, α,ω-dicarboxylic acids, single-cell proteins, and more, making it an attractive target for biotechnological applications. This review provides an update on C. tropicalis biological characteristics and its efficiency in producing a diverse range of biomolecules with industrial significance from various feedstocks. The information presented in this review contributes to a better understanding of C. tropicalis and highlights its potential for biotechnological applications and market viability.

摘要

热带假丝酵母是一种具有医学和工业意义的非常规酵母,属于CTG进化枝。全基因组测序和遗传分析的最新进展揭示了它与其他具有生物技术重要性的非常规酵母的密切关系。热带假丝酵母以其在合成各种有价值的生物分子方面的巨大潜力而闻名,如乙醇、木糖醇、生物表面活性剂、脂质、酶、α,ω-二羧酸、单细胞蛋白等,这使其成为生物技术应用的一个有吸引力的目标。本文综述了热带假丝酵母的生物学特性及其从各种原料生产多种具有工业意义的生物分子的效率。本文提供的数据有助于更好地了解热带假丝酵母,并突出其在生物技术应用和市场可行性方面的潜力。

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