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Endothelial Progenitor Cell (EPC) is a Prime Target in Diabetic Wound Healing: Mechanisms and Target Therapies.

作者信息

Markandeywar Tanmay Sudhakar, Singh Dilpreet, Singh Gurmeet, Kurmi Balak Das, Narang Raj Kumar

机构信息

IK Gujral Punjab Technical University, Kapurthala, 144603, Jalandhar Punjab, India.

Department of Pharmaceutics, ISF College of Pharmacy (An Autonomous College), Moga, 142001, Punjab, India.

出版信息

Curr Mol Med. 2024;24(9):1073-1076. doi: 10.2174/1566524023666230911141402.

DOI:10.2174/1566524023666230911141402
PMID:37694783
Abstract
摘要

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The effect of estrogen on diabetic wound healing is mediated through increasing the function of various bone marrow-derived progenitor cells.雌激素对糖尿病伤口愈合的作用是通过增强各种骨髓来源祖细胞的功能来介导的。
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Bee Venom Accelerates Wound Healing in Diabetic Mice by Suppressing Activating Transcription Factor-3 (ATF-3) and Inducible Nitric Oxide Synthase (iNOS)-Mediated Oxidative Stress and Recruiting Bone Marrow-Derived Endothelial Progenitor Cells.蜂毒通过抑制激活转录因子-3（ATF-3）和诱导型一氧化氮合酶（iNOS）介导的氧化应激以及募集骨髓来源的内皮祖细胞来加速糖尿病小鼠的伤口愈合。
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本文引用的文献

1
Carvacrol Improves Vascular Function in Hypertensive Animals by Modulating Endothelial Progenitor Cells.香芹酚通过调节内皮祖细胞改善高血压动物的血管功能。
Nutrients. 2023 Jul 4;15(13):3032. doi: 10.3390/nu15133032.
2
Loxenatide attenuates ROS-mediated vascular endothelial progenitor cell damage and mitochondrial dysfunction via SIRT3/Foxo3 signaling pathway.洛塞那肽通过 SIRT3/Foxo3 信号通路减轻 ROS 介导的血管内皮祖细胞损伤和线粒体功能障碍。
J Biochem Mol Toxicol. 2023 Nov;37(11):e23452. doi: 10.1002/jbt.23452. Epub 2023 Jul 7.
3
Regulation of endothelial progenitor cell functions during hyperglycemia: new therapeutic targets in diabetic wound healing.
高血糖症对内皮祖细胞功能的调控：糖尿病创面愈合中新的治疗靶点。
J Mol Med (Berl). 2022 Apr;100(4):485-498. doi: 10.1007/s00109-021-02172-1. Epub 2022 Jan 8.
4
miRNA-221-3p in Endothelial Progenitor Cell-Derived Exosomes Accelerates Skin Wound Healing in Diabetic Mice.内皮祖细胞衍生外泌体中的miRNA-221-3p加速糖尿病小鼠皮肤伤口愈合
Diabetes Metab Syndr Obes. 2020 Apr 22;13:1259-1270. doi: 10.2147/DMSO.S243549. eCollection 2020.
5
Endothelial progenitor cell therapy for chronic wound tissue regeneration.内皮祖细胞治疗慢性创面组织再生。
Cytotherapy. 2019 Nov;21(11):1137-1150. doi: 10.1016/j.jcyt.2019.09.002. Epub 2019 Oct 23.
6
Dysfunction and Therapeutic Potential of Endothelial Progenitor Cells in Diabetes Mellitus.糖尿病中内皮祖细胞的功能障碍与治疗潜力
J Clin Med Res. 2018 Oct;10(10):752-757. doi: 10.14740/jocmr3581w. Epub 2018 Sep 10.
7
Endothelial Progenitor Cells: New Targets for Therapeutics for Inflammatory Conditions With High Cardiovascular Risk.内皮祖细胞：高心血管风险炎症性疾病治疗的新靶点。
Front Med (Lausanne). 2018 Jul 10;5:200. doi: 10.3389/fmed.2018.00200. eCollection 2018.
8
Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder.药物调控内皮祖细胞对糖尿病及糖尿病相关疾病的多重治疗作用。
J Transl Med. 2017 Aug 31;15(1):185. doi: 10.1186/s12967-017-1280-y.
9
High glucose-induced endothelial progenitor cell dysfunction.高糖诱导的内皮祖细胞功能障碍。
Diab Vasc Dis Res. 2017 Sep;14(5):381-394. doi: 10.1177/1479164117719058. Epub 2017 Jul 18.
10
Injectable shear-thinning hydrogels used to deliver endothelial progenitor cells, enhance cell engraftment, and improve ischemic myocardium.用于递送内皮祖细胞、增强细胞植入并改善缺血心肌的可注射剪切变稀水凝胶。
J Thorac Cardiovasc Surg. 2015 Nov;150(5):1268-76. doi: 10.1016/j.jtcvs.2015.07.035. Epub 2015 Jul 17.