Payne J E, Chapuis P H, Pheils M T
Dis Colon Rectum. 1986 Nov;29(11):733-7. doi: 10.1007/BF02555321.
Three hundred ten predominantly male patients who were 75 years of age or older and had surgery for colorectal carcinoma had a hospital mortality rate of 9 percent and a cancer-related five-year survival of 50 percent. These results and a detailed analysis of the causes of complications and mortality were compared with the outcome of 710 patients who were treated concurrently and who were younger than 75 years. Tumors in older patients had a tendency to occur on the right side and were more locally advanced. Increased mortality was particularly attributable to sepsis and cardiovascular causes. Increased morbidity was due principally to respiratory and urinary problems. There were no significant differences, however, in wound or anastomotic complications, nor was therapy for the older patients more costly. The indications for surgical resection for colorectal cancer in patients aged 75 years and older should be the same as those for any younger group.
310名年龄在75岁及以上且因结直肠癌接受手术的男性患者，其医院死亡率为9%，与癌症相关的五年生存率为50%。将这些结果以及对并发症和死亡原因的详细分析，与同期接受治疗且年龄小于75岁的710名患者的结果进行了比较。老年患者的肿瘤倾向于发生在右侧，且局部进展程度更高。死亡率增加尤其归因于败血症和心血管原因。发病率增加主要是由于呼吸和泌尿系统问题。然而，伤口或吻合口并发症并无显著差异，老年患者的治疗费用也没有更高。75岁及以上患者结直肠癌手术切除的指征应与任何年轻组相同。
