Irvin G L, Robinson D S, Hubbard S
Am Surg. 1985 Jul;51(7):418-22.
This study emphasizes the risks in the operative treatment of patients with colorectal cancer. In dissecting our overall operative mortality of 7.4 per cent in consecutive patients over a 5-year period, three factors influencing the outcome were identified. These were the age of the patient, the stage of the disease, and the availability of preoperative bowel preparation by mechanical cleansing and antibiotic suppression of the colonic bacterial flora. Earlier diagnosis and elective resection of prepared bowel offers marked improvement in the operative risk for patients with colorectal cancer.
本研究强调了结直肠癌患者手术治疗中的风险。在剖析我们5年间连续患者7.4%的总体手术死亡率时,确定了影响预后的三个因素。这些因素是患者的年龄、疾病分期以及通过机械清洁和抗生素抑制结肠菌群进行术前肠道准备的可行性。早期诊断并对准备好的肠道进行择期切除,可显著改善结直肠癌患者的手术风险。