Anino Calvince Otieno, Wandera Immaculate, Masimba Zachary Ondicho, Kirui Collins Kipkosgei, Makero Carjetine Syallow, Omari Phanice Kerubo, Sanga Philip
University of Kabianga, Kericho, Kenya.
Ministry of Health, Baringo, Kenya.
PLOS Glob Public Health. 2023 Sep 12;3(9):e0001562. doi: 10.1371/journal.pgph.0001562. eCollection 2023.
Hesitancy to Covid-19 vaccine is a global challenge despite the compelling evidence of the value of vaccine in preventing disease and saving lives. It is suggested that context-specific strategies can enhance acceptability and decrease hesitancy to Covid-19 vaccine. Hence, the study determined uptake and determinants of Covid-19 vaccine following a sustained voluntary vaccination drive by Kenyan government. We conducted institution based cross-sectional survey of 1244 elderly persons aged 58 to 98 years in the months of January, February and March, 2022. A multinomial logistic regression analysis was used to investigate determinants of Covid 19 vaccine uptake. The predictor variables included socioeconomic and demographic characteristics, convenience and ease of access of the vaccine, collective responsibility, complacency and the three dimensions of confidence; trust in safety, trust in decision makers and delivery system. The findings are reported as the adjusted odd ratio (AOR) at 95% confidence interval (CI). Significant level was considered at p <0.05. The results from the multinomial logistic regression analysis indicated that advanced age and presence of chronic disease were associated with increased odds of doubt on Covid 19 vaccine, while long distance from vaccination centers was associated with increased odds of delay in vaccination. Overall, the findings of this study provided valuable insights into the factors influencing vaccine hesitancy among the elderly population in Kenya and will inform the development of targeted interventions to increase vaccine acceptance and uptake in this population.
尽管有令人信服的证据表明新冠疫苗在预防疾病和拯救生命方面具有价值，但对新冠疫苗的犹豫仍然是一个全球性挑战。有人认为，因地制宜的策略可以提高新冠疫苗的可接受性并减少人们的犹豫。因此，本研究在肯尼亚政府持续开展自愿疫苗接种活动之后，确定了新冠疫苗的接种情况及其决定因素。我们于2022年1月、2月和3月对1244名年龄在58至98岁之间的老年人进行了基于机构的横断面调查。采用多项逻辑回归分析来研究新冠疫苗接种的决定因素。预测变量包括社会经济和人口特征、疫苗的便利性和可及性、集体责任、自满情绪以及信心的三个维度；对安全性的信任、对决策者和接种系统的信任。研究结果以95%置信区间（CI）的调整优势比（AOR）报告。显著性水平设定为p<0.05。多项逻辑回归分析的结果表明，高龄和患有慢性病与对新冠疫苗产生怀疑的几率增加有关，而距离疫苗接种中心较远则与延迟接种的几率增加有关。总体而言，本研究结果为影响肯尼亚老年人群体疫苗犹豫的因素提供了有价值的见解，并将为制定有针对性的干预措施提供依据，以提高该人群对疫苗的接受度和接种率。
