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季节性超急性全葡萄膜炎(SHAPU)在 COVID-19 大流行期间爆发。

Seasonal Hyperacute Panuveitis (SHAPU) Outbreak Amidst COVID-19 Pandemic.

机构信息

Himalaya Eye Hospital, Eye Care Foundation, Pokhara University, Pokhara, Nepal.

Department of Ophthalmology, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, B. P. Koirala Lions Centre for Ophthalmic Studies, Maharajgunj, Kathmandu, Nepal.

出版信息

Ocul Immunol Inflamm. 2024 Sep;32(7):1400-1404. doi: 10.1080/09273948.2023.2250440. Epub 2023 Sep 12.

DOI:10.1080/09273948.2023.2250440
PMID:37699175
Abstract

PURPOSE

To document the demographic profile of the SHAPU outbreak amidst the COVID-19 pandemic.

METHODS

A multicentric cross-sectional study of the 2021 SHAPU outbreak during the second phase of the COVID-19 outbreak.

RESULTS

A total of 135 patients were diagnosed with SHAPU from August to December 2021, 77 (57%) were children <16 years, males 54.8% and 34.8% had direct physical contact with white moths and 41.5% had severe type of SHAPU. Dramatic increment in the moth abundance was noted in these outbreak sites. Few cases presented with atypical ocular findings, unlike past outbreaks. Due to the ongoing COVID-19 pandemic with restrictions on travel and transportation, timely management was difficult and good visual outcome was achieved only in mild-moderate cases with an early presentation.

CONCLUSION

The surge in the number of SHAPU patients, its occurrence in areas previously unreported, and some atypical presentation added raised suspicion of a possible link between COVID-19 and SHAPU.

摘要

目的

记录 COVID-19 大流行期间 SHAPU 疫情的人口统计学特征。

方法

这是一项在 COVID-19 大流行第二阶段针对 2021 年 SHAPU 疫情的多中心横断面研究。

结果

2021 年 8 月至 12 月期间,共诊断出 135 例 SHAPU 患者,77 例(57%)为<16 岁的儿童,男性占 54.8%,34.8%有与白蛾的直接身体接触,41.5%为 SHAPU 重型。在这些疫情发生地,发现蛾的数量急剧增加。与过去的疫情不同,少数病例表现出不典型的眼部表现。由于 COVID-19 大流行期间旅行和交通受到限制,及时管理变得困难,只有轻度至中度病例且早期就诊才能获得良好的视力预后。

结论

SHAPU 患者数量的增加、其在以前未报告的地区出现以及一些不典型表现增加,这引发了对 COVID-19 与 SHAPU 之间可能存在联系的怀疑。

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Seasonal Hyperacute Panuveitis (SHAPU) Outbreak Amidst COVID-19 Pandemic.季节性超急性全葡萄膜炎(SHAPU)在 COVID-19 大流行期间爆发。
Ocul Immunol Inflamm. 2024 Sep;32(7):1400-1404. doi: 10.1080/09273948.2023.2250440. Epub 2023 Sep 12.
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