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用于严重肢体缺血姑息治疗的连续隧道式锁骨下神经导管:病例报告

Continuous Tunneled Infraclavicular Nerve Catheter for Palliative Management of Critical Limb Ischemia: A Case Report.

作者信息

Yek Jia Lin Jacklyn, Oey Nicodemus, Jain Amit, Liu Christopher, Angamuthu Nithia

机构信息

Department of Anaesthesiology and Perioperative Medicine and Singapore General Hospital, Singapore, Singapore.

Department of Rehabilitation Medicine, Singapore General Hospital, Singapore, Singapore.

出版信息

J Palliat Med. 2023 Nov;26(11):1551-1554. doi: 10.1089/jpm.2023.0212. Epub 2023 Sep 12.

Abstract

Critical limb ischemia (CLI) is limb pain occurring at rest or impending limb loss as a result of lack of blood flow to the affected extremity. CLI pain is challenging to control despite multimodal pharmacologic analgesia and surgical intervention. We describe the successful use of a continuous local anesthetic infusion via an infraclavicular nerve catheter to control severe refractory ischemic upper limb pain in a patient with metastatic lung cancer for whom surgical and pharmacological intervention was unsuccessful. As her opioid requirements increased due to worsening ischemic pain, she subsequently developed opioid toxicity, hence prompting the palliative use of a tunneled infraclavicular nerve catheter under ultrasound guidance to minimize opioid requirements. Her opioid requirements tailed down subsequently with the successful insertion of the infraclavicular nerve catheter and she remained pain free till her death. Palliative use of nerve catheters is a safe and an effective alternative in patients with refractory cancer pain, and we describe our methods to prolong its use and minimizing its associated long-term complications.

摘要

严重肢体缺血(CLI)是指由于受影响肢体血流不足而导致的静息时肢体疼痛或即将发生的肢体丧失。尽管采用了多模式药物镇痛和手术干预,CLI疼痛仍难以控制。我们描述了通过锁骨下神经导管持续输注局麻药成功控制一名转移性肺癌患者严重难治性缺血性上肢疼痛的案例,该患者的手术和药物干预均未成功。由于缺血性疼痛加剧,她对阿片类药物的需求增加,随后出现了阿片类药物毒性,因此促使在超声引导下通过隧道式锁骨下神经导管进行姑息治疗,以尽量减少阿片类药物的需求。随着锁骨下神经导管成功插入,她对阿片类药物的需求随后减少,直至去世前一直无痛。对于难治性癌痛患者,姑息性使用神经导管是一种安全有效的替代方法,我们描述了延长其使用时间并尽量减少其相关长期并发症的方法。

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