N-吡啶甲基-3,5-二甲基苯甲酰胺的“体外”代谢
'In vitro' metabolism of N-picolyl-3,5-dimethylbenzamides.
作者信息
Caputo O, Viola F, Grosa G, Rocco F, Biglino G
出版信息
Eur J Drug Metab Pharmacokinet. 1986 Apr-Jun;11(2):91-9. doi: 10.1007/BF03189833.
PMID:3770019
Abstract
'In vitro' metabolism of three isomeric N-picolyl-3,5-dimethylbenzamides was studied. The metabolites were isolated through TLC and HPLC techniques and identified by direct comparison with authentic compounds. The results of phenobarbital and 3-methyl-cholantrene inductions are given.
摘要
研究了三种异构的N-吡啶甲基-3,5-二甲基苯甲酰胺的“体外”代谢。通过薄层色谱法（TLC）和高效液相色谱法（HPLC）技术分离代谢产物，并通过与标准化合物直接比较进行鉴定。给出了苯巴比妥和3-甲基胆蒽诱导的结果。
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