Chatelain J, Baron H, Baille V, Bourdonnais A, Delasnerie-Laupretre N, Cathala F
Eur J Epidemiol. 1986 Mar;2(1):31-5. doi: 10.1007/BF00152714.
An "Ile de France" flock was studied over a period of 5 years. The authors found similar results concerning incidence and age of onset of scrapie to those found in the English literature. A close relationship was established between the age of the dam at parturition and the age of the progeny at onset of scrapie. In the later years of our study, scrapie was detected in younger animals than in the earlier years, suggesting a phenomenon of genetic "anticipation". Increased fecundity in this endemically affected flock might represent a form of selection which favorises the occurrence and maintenance of the disease within the flock.
对一群“法兰西岛”绵羊进行了为期5年的研究。作者发现，羊瘙痒病的发病率和发病年龄与英国文献中的结果相似。分娩时母羊的年龄与羊瘙痒病发病时后代的年龄之间建立了密切关系。在我们研究的后期，与早期相比，在更年轻的动物中检测到了羊瘙痒病，这表明存在遗传“早现”现象。在这个地方性感染的羊群中，繁殖力增加可能代表了一种选择形式，有利于疾病在羊群中的发生和维持。
