Wang Lan-Jing, Yao Xin, Qi Qi, Qin Jian-Ping
Department of Gastroenterology, The General Hospital of Western Theater Command, Chengdu 610083, Sichuan Province, China.
World J Gastrointest Surg. 2023 Aug 27;15(8):1564-1573. doi: 10.4240/wjgs.v15.i8.1564.
Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for treating the complications of portal hypertension in liver cirrhosis. While the pathogenesis of postoperative TIPS-related hepatic encephalopathy (HE) has yet to be fully understood, intraoperative portosystemic shunts may provide a pathological basis for the occurrence of postoperative HE in patients with liver cirrhosis. Studies at home and abroad have expressed mixed opinions about TIPS-related HE. This study presents a literature review on the risk factors for and prevention and treatment of perioperative TIPS-related HE in patients with liver cirrhosis, aiming to optimize the procedure and reduce the incidence of postoperative HE.
经颈静脉肝内门体分流术(TIPS)是治疗肝硬化门静脉高压并发症的一种成熟手术。虽然术后TIPS相关肝性脑病(HE)的发病机制尚未完全明确,但术中门体分流可能为肝硬化患者术后HE的发生提供病理基础。国内外研究对TIPS相关HE的看法不一。本研究对肝硬化患者围手术期TIPS相关HE的危险因素及防治进行文献综述,旨在优化手术操作并降低术后HE的发生率。