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经颈静脉肝内门体分流术围手术期肝性脑病的防治

Prevention and treatment of hepatic encephalopathy during the perioperative period of transjugular intrahepatic portosystemic shunt.

作者信息

Wang Lan-Jing, Yao Xin, Qi Qi, Qin Jian-Ping

机构信息

Department of Gastroenterology, The General Hospital of Western Theater Command, Chengdu 610083, Sichuan Province, China.

出版信息

World J Gastrointest Surg. 2023 Aug 27;15(8):1564-1573. doi: 10.4240/wjgs.v15.i8.1564.

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for treating the complications of portal hypertension in liver cirrhosis. While the pathogenesis of postoperative TIPS-related hepatic encephalopathy (HE) has yet to be fully understood, intraoperative portosystemic shunts may provide a pathological basis for the occurrence of postoperative HE in patients with liver cirrhosis. Studies at home and abroad have expressed mixed opinions about TIPS-related HE. This study presents a literature review on the risk factors for and prevention and treatment of perioperative TIPS-related HE in patients with liver cirrhosis, aiming to optimize the procedure and reduce the incidence of postoperative HE.

摘要

经颈静脉肝内门体分流术(TIPS)是治疗肝硬化门静脉高压并发症的一种成熟手术。虽然术后TIPS相关肝性脑病(HE)的发病机制尚未完全明确,但术中门体分流可能为肝硬化患者术后HE的发生提供病理基础。国内外研究对TIPS相关HE的看法不一。本研究对肝硬化患者围手术期TIPS相关HE的危险因素及防治进行文献综述,旨在优化手术操作并降低术后HE的发生率。

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本文引用的文献

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EASL Clinical Practice Guidelines on the management of hepatic encephalopathy.EASL 临床实践指南:肝性脑病管理。
J Hepatol. 2022 Sep;77(3):807-824. doi: 10.1016/j.jhep.2022.06.001. Epub 2022 Jun 17.
8
Baveno VII - Renewing consensus in portal hypertension.《巴韦诺 VII 共识:门静脉高压领域的新共识》
J Hepatol. 2022 Apr;76(4):959-974. doi: 10.1016/j.jhep.2021.12.022. Epub 2021 Dec 30.

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