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一项探索体质与类风湿关节炎关联的病例对照研究。

A case-control study for exploring the association of Prakriti with Rheumatoid Arthritis.

作者信息

Chinthala Rajkumar, Baghel Arjun Singh, Shubhangi Kamble, Bhagavathi N N L

机构信息

Department of Samhita & Siddhanta, TTD's SV Ayurvedic College, A Constituent Educational Institute of Tirumala Tirupathi Devasthanams, Tirupathi, Andhra Pradesh, 517507, India.

Department of Basic Principles, Institute of Teaching and Research in Ayurveda, Jamnagar, 361008, India.

出版信息

J Ayurveda Integr Med. 2023 Sep-Oct;14(5):100789. doi: 10.1016/j.jaim.2023.100789. Epub 2023 Sep 11.

DOI:10.1016/j.jaim.2023.100789
PMID:37703672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10505973/
Abstract

BACKGROUND

Deha-Prakriti (DP) is a unique contribution of Ayurveda, which distinguishes the population into three main groups viz., Vata, Pitta, and Kapha predominant individuals. Its assessment helps physicians to prescribe a suitable diet, daily regimen, and lifestyle that prevents non-communicable diseases. Amavata (Rheumatoid Arthritis) is a disease that needs personalized management approach.

AIM

To evaluate the association of DP with Amavata (∼Rheumatoid Arthritis).

OBJECTIVE

To evaluate DP-based susceptibility in the manifestation of Amavata vis-à-vis Rheumatoid Arthritis.

METHODOLOGY

A case-control study was conducted from 18.04.2018 to 09.01.2020, involving 150 cases (patients of Amavata), and 150 controls (healthy volunteers), matching in age (between 18 to 50 years), and sex, selected from Jamnagar. CCRAS-PAS for both the groups, Health Assessment proforma of TRISUTRA project CSIR-AYURGENOMICS, were used. Logistic regression analyses were conducted to determine the relationship between DP and Amavata.

RESULTS

The proportion of people with Vata dosha in the case group (53.79%) was substantially higher (P < 0.0001) than in the control group (24.91%). Pitta (39.35%) and Kapha (36.27%) doshas were found to be more prevalent in the control group (P < 0.0001). There was a six-percent rise in the likelihood of developing Amavata with every unit increase in Vata percentage, according to logistic regression analysis.

CONCLUSION

Vata predominant DP has a significant association with Amavata. Vata predominant DP individuals are more susceptible to Amavata than Pitta and Kapha predominant DP individuals.

摘要

背景

体质分型是阿育吠陀医学的一项独特贡献,它将人群分为三大主要类型,即风型、火型和水型为主的个体。对其进行评估有助于医生制定合适的饮食、日常养生法和生活方式,以预防非传染性疾病。类风湿关节炎是一种需要个性化管理方法的疾病。

目的

评估体质分型与类风湿关节炎的关联。

目标

评估基于体质分型的类风湿关节炎发病易感性。

方法

于2018年4月18日至2020年1月9日进行了一项病例对照研究,纳入150例病例(类风湿关节炎患者)和150例对照(健康志愿者),年龄(18至50岁)和性别相匹配,均选自贾姆讷格尔。两组均使用了全印阿育吠陀医学中央理事会 - 全印阿育吠陀医学研究计划(CCRAS - PAS)以及印度科学与工业研究理事会 - 阿育吠陀基因组学(CSIR - AYURGENOMICS)项目的健康评估表。进行逻辑回归分析以确定体质分型与类风湿关节炎之间的关系。

结果

病例组中风型体质者的比例(53.79%)显著高于对照组(24.91%)(P < 0.0001)。火型(39.35%)和水型(36.27%)体质在对照组中更为普遍(P < 0.0001)。根据逻辑回归分析,风型百分比每增加一个单位,患类风湿关节炎的可能性就增加6%。

结论

风型为主的体质分型与类风湿关节炎有显著关联。风型为主体质分型的个体比火型和水型为主体质分型的个体更容易患类风湿关节炎。

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