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不同类型牛奶对儿童唾液pH值的影响:一项初步随机对照交叉试验

Effect of various types of milk on salivary pH among children: a pilot randomized controlled crossover trial.

作者信息

Zamzam Rouaa, Karkoutly Mawia, Bshara Nada

机构信息

Pediatric Dentistry Department, Faculty of Dentistry, Damascus University, Damascus, Syria.

出版信息

BDJ Open. 2023 Sep 13;9(1):44. doi: 10.1038/s41405-023-00170-8.

DOI:10.1038/s41405-023-00170-8
PMID:37704635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10500012/
Abstract

OBJECTIVE

This study aimed to evaluate salivary pH changes after consuming three types of milk in children aged 3-5 years. The null hypothesis was that no statistically significant difference would be noted in the salivary pH between high-protein, full-fat, and sweetened milk groups at different time points.

MATERIALS AND METHODS

This was a double-blind, pilot randomized controlled crossover trial. 30 Children have undergone three experimental sessions with a 1-week washout period. Each child was given 250 mL of one of the following types of milk: high-protein, full-fat, or sweetened milk. The salivary pH was measured at the baseline (t) after 5 (t), 10 (t), 15 (t), 30 (t), and 60 (t) minutes of milk consumption, using a pH saliva indicator strip.

RESULTS

There is a sharp drop in salivary pH after 5 min of sweetened (P < 0.05) and full-fat milk consumption (p < 0.05). However, the initial drop in the salivary pH was found to remain above the critical level. For the high-protein milk group, salivary pH decreased slightly after 5 min but was similar to that at the baseline (p = 0.573). In the high-protein milk group (p < 0.05), the salivary pH was slightly greater than the baseline value at t.

CONCLUSIONS

The study shows an initial suggestion that milk is a non-cariogenic beverage, even when sugar is added. Furthermore, high-protein milk has a protective effect from dental caries.

摘要

目的

本研究旨在评估3至5岁儿童饮用三种类型的牛奶后唾液pH值的变化。无效假设是在不同时间点,高蛋白、全脂和甜牛奶组之间的唾液pH值无统计学显著差异。

材料与方法

这是一项双盲、先导性随机对照交叉试验。30名儿童接受了三个实验阶段,中间有1周的洗脱期。每个儿童被给予250毫升以下类型的牛奶之一:高蛋白、全脂或甜牛奶。在饮用牛奶后5分钟(t)、10分钟(t)、15分钟(t)、30分钟(t)和60分钟(t)时,使用pH唾液试纸条在基线(t)测量唾液pH值。

结果

饮用甜牛奶(P < 0.05)和全脂牛奶(p < 0.05)5分钟后,唾液pH值急剧下降。然而,发现唾液pH值的初始下降仍高于临界水平。对于高蛋白牛奶组,饮用5分钟后唾液pH值略有下降,但与基线时相似(p = 0.573)。在高蛋白牛奶组(p < 0.05)中,t时刻的唾液pH值略高于基线值。

结论

该研究初步表明,即使添加了糖,牛奶也是一种非致龋性饮料。此外,高蛋白牛奶对龋齿有保护作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/117b/10500012/3c49ca2854dd/41405_2023_170_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/117b/10500012/3bed59d3b5b6/41405_2023_170_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/117b/10500012/3c49ca2854dd/41405_2023_170_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/117b/10500012/3bed59d3b5b6/41405_2023_170_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/117b/10500012/3c49ca2854dd/41405_2023_170_Fig2_HTML.jpg

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BDJ Open. 2023 Apr 11;9(1):16. doi: 10.1038/s41405-023-00141-z.
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