Peters G, Schumacher-Perdreau F, Pulverer G
Immun Infekt. 1986 Sep;14(5):165-9.
Coagulase-negative staphylococci are important members of the normal aerobic microflora of human skin and mucous membranes. Normally they are not pathogenic for men. But the increase in patients with implanted plastic foreign bodies or intravascular catheters had led to a dramatic change. In these patients, coagulase-negative staphylococci are the predominant organisms causing septicemia. Special pathomechanisms are involved in the colonization of polymers by staphylococci leading to a "plastic infection". Intravascular catheters are also important factors in the origin of septicemia in premature neonates and in patients with malignant diseases, especially under cytostatic therapy. Premature or suppressed opsonophagocytosis mechanisms are responsible for the origin and maintainance of septicemia.
凝固酶阴性葡萄球菌是人类皮肤和黏膜需氧正常微生物群的重要成员。通常情况下，它们对人类无致病性。但植入塑料异物或血管内导管的患者数量增加，导致了情况的显著变化。在这些患者中，凝固酶阴性葡萄球菌是引起败血症的主要病原体。葡萄球菌在聚合物上定植导致“塑料感染”，涉及特殊的发病机制。血管内导管也是早产儿和恶性疾病患者，尤其是接受细胞抑制疗法患者发生败血症的重要因素。过早或受抑制的调理吞噬作用机制是败血症发生和持续存在的原因。
