University of Texas at El Paso, 500 University Ave, El Paso, Texas, 79968, USA.
School of Public Health, Dept. of Health Promotion and Behavioral Sciences, The University of Texas Health Science Center at Houston (UTHealth), El Paso Campus, 5130 Gateway East Blvd, El Paso, TX, 79905, USA.
BMC Public Health. 2023 Sep 14;23(1):1781. doi: 10.1186/s12889-023-16628-1.
Human papillomavirus (HPV) is the most common sexually transmitted infection and is associated with many types of cancers that disproportionately impact Hispanics. An HPV vaccine is available for individuals ages 9-45 that can prevent up to 90% of HPV-associated cancers. The current study investigates factors associated with accepting the HPV vaccine in a predominately Hispanic community.
A cross-sectional study design with an online questionnaire was used to collect data from a community sample of adults between the ages 18-65 residing in a U.S./Mexico border city, El Paso, Texas. Theory-based factors (e.g., the Health Belief Model), culture-based factors (e.g., familism), and trusted sources of information were examined as predictors of HPV-vaccine acceptance (HPV-VA) and HPV-vaccine uptake (HPV-VU).
Community members (N = 602, M = 34.65, SD = 9.79) who were predominately Hispanic (89.4%) and female (79.6%) participated in the study. Linear regression models revealed that HPV-VA was associated with household size, primary language, engagement in organizational activities, health-related community stigma, government trust, and the HBM theory-based factors: perceived benefits, perceived harm, and perceived severity. Logistic regression analyses revealed that HPV-VU was associated with household size, engagement in non-organizational activities, HPV trusted sources of information, and perceived safety.
Adequate HPV vaccination uptake among all vaccine-eligible Hispanics is an important step to lessen the HPV-attributed cancer burden. Our hypothesis that theory-based factors would be associated with HPV-VA and HPV-VU was supported. Our findings have implications for designing trusted, theory-based, and culturally sensitive health communications and interventions to promote vaccines in minority underrepresented communities.
人乳头瘤病毒（HPV）是最常见的性传播感染，与许多类型的癌症有关，这些癌症对西班牙裔人群的影响不成比例。目前有一种 HPV 疫苗可供 9-45 岁的人群使用，可预防高达 90%的 HPV 相关癌症。本研究调查了在以西班牙裔为主的社区中，与接受 HPV 疫苗相关的因素。
采用横断面研究设计，通过在线问卷收集了居住在美国/墨西哥边境城市得克萨斯州埃尔帕索的 18-65 岁成年人社区样本的数据。以理论为基础的因素（如健康信念模型）、文化因素（如家庭主义）和可信赖的信息来源被视为 HPV 疫苗接种接受度（HPV-VA）和 HPV 疫苗接种率（HPV-VU）的预测因素。
社区成员（N=602，M=34.65，SD=9.79）主要是西班牙裔（89.4%）和女性（79.6%）。线性回归模型显示，HPV-VA 与家庭规模、主要语言、参与组织活动、与健康相关的社区耻辱感、政府信任以及基于 HBM 理论的因素（感知益处、感知危害和感知严重性）有关。逻辑回归分析显示，HPV-VU 与家庭规模、参与非组织活动、HPV 可信信息来源以及感知安全性有关。
所有符合 HPV 疫苗接种条件的西班牙裔人群充分接种 HPV 疫苗是减轻 HPV 相关癌症负担的重要步骤。我们的假设是，基于理论的因素与 HPV-VA 和 HPV-VU 有关，这一假设得到了支持。我们的研究结果对设计可信的、基于理论的和具有文化敏感性的健康传播和干预措施以促进少数民族代表性不足的社区接种疫苗具有重要意义。
