Alkhatatba Mohammad, Abualadas Jehad, Tabar Malik Alansari Abu, Abueed Mutaz, Alghzawi Ahmad Abdalmajeed, Abualadas Rawan, Radaideh Ahmad, Essa Suhaib Bani, Obeidat Naser, Alma Aiteh Ala A, Al-Omari Jamal
Department of Special Surgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Department of Public Health, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Acta Inform Med. 2023 Jun;31(2):111-114. doi: 10.5455/aim.2023.31.111-114.
Osteoarthritis of the knee (OA) and osteoporosis are two conditions that have a significant impact on society, have a great impact on quality of life, and can lead to functional impairment. However, the relationship between knee OA and osteoporosis is unclear.
The aim of this study was to examine if there is a link between symptomatic advanced knee osteoarthritis and low bone mineral density.
A total of 430 patients with symptomatic and advanced radiographic knee OA served as participants in this study. Plain radiographs were used to screen participants for osteoarthritis, and a Dual Energy X-ray Absorptiometry (DEXA) scan was used to determine each participant's bone mineral density (BMD).
The lumbar spine, whole femur, and femoral neck BMD levels were statistically higher in the early OA (Kelldren-Lawrence (KL) I and II) group compared with the advanced (III and IV) OA group. Higher BMD at the whole femur and femoral neck but not at the lumbar spine was observed when comparing patients with grades I, II, and III with patients with grade IV after adjustment for body mass index.
The findings of this study indicate that the degree of knee OA is correlated with a decline in BMD. These findings lend credence to the theory that the two conditions may be linked to one another. Our study concluded that patients with advanced knee osteoarthritis are at risk of developing osteoporosis. As a result, orthopedic doctors are required to screen for osteoporosis in patients with advanced knee osteoarthritis to both prevent and treat osteoporosis at an earlier stage.
膝关节骨关节炎（OA）和骨质疏松症是两种对社会有重大影响、对生活质量有极大影响且可导致功能障碍的病症。然而，膝关节OA与骨质疏松症之间的关系尚不清楚。
本研究的目的是检验有症状的晚期膝关节骨关节炎与低骨密度之间是否存在关联。
本研究共纳入430例有症状且X线片显示为晚期膝关节OA的患者。采用普通X线片筛查骨关节炎患者，并使用双能X线吸收法（DEXA）扫描测定每位参与者的骨密度（BMD）。
早期OA（凯尔格伦-劳伦斯（KL）I级和II级）组的腰椎、全股骨和股骨颈BMD水平在统计学上高于晚期（III级和IV级）OA组。在调整体重指数后，将I级、II级和III级患者与IV级患者进行比较时，观察到全股骨和股骨颈的BMD较高，但腰椎的BMD未升高。
本研究结果表明，膝关节OA的程度与BMD下降相关。这些发现支持了这两种病症可能相互关联的理论。我们的研究得出结论，晚期膝关节骨关节炎患者有患骨质疏松症的风险。因此，骨科医生需要对晚期膝关节骨关节炎患者进行骨质疏松症筛查，以便在早期预防和治疗骨质疏松症。
