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近场投影光学显微镜(NPOM)作为一种用于纳米级超分辨成像的新方法。

Near-field projection optical microscope (NPOM) as a new approach to nanoscale super-resolved imaging.

作者信息

Sanjeev Abhijit, Glukhov David, Salahudeen Rafeeka Rinsa, Karsenty Avi, Zalevsky Zeev

机构信息

Faculty of Engineering, Bar-Ilan University, 5290002, Ramat Gan, Israel.

Nanotechnology Center, Bar-Ilan University, 5290002, Ramat Gan, Israel.

出版信息

Sci Rep. 2023 Sep 16;13(1):15408. doi: 10.1038/s41598-023-41978-6.

Abstract

A new super-resolution method, entitled Near-field Projection Optical Microscopy (NPOM), is presented. This novel technique enables the imaging of nanoscale objects without the need for surface scanning, as is usually required in existing methods such as NSOM (near-field scanning optical microscope). The main advantage of the proposed concept, besides the elimination of the need for a mechanical scanning mechanism, is that the full field of regard/view is imaged simultaneously and not point-by-point as in scanning-based techniques. Furthermore, by using compressed sensing, the number of projected patterns needed to decompose the spatial information of the inspected object can be made smaller than the obtainable points of spatial resolution. In addition to the development of mathematical formalism, this paper presents the results of a series of complementary numerical tests, using various objects and patterns, that were performed to verify the accuracy of the reconstruction capabilities. We have also performed a proof of concept experiment to support the numerical formalism.

摘要

本文提出了一种名为近场投影光学显微镜(NPOM)的新型超分辨率方法。这项新技术能够对纳米级物体进行成像,而无需像现有方法如近场扫描光学显微镜(NSOM)那样进行表面扫描。除了无需机械扫描机制外,该方法的主要优势在于能同时对整个视场进行成像,而不像基于扫描的技术那样逐点成像。此外,通过使用压缩感知,分解被检查物体空间信息所需的投影图案数量可以小于可获得的空间分辨率点数。除了数学形式的发展,本文还展示了一系列补充数值测试的结果,这些测试使用了各种物体和图案,以验证重建能力的准确性。我们还进行了概念验证实验来支持数值形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37dd/10505152/d8f662756467/41598_2023_41978_Fig1_HTML.jpg

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