Varghese Eleesha A, Zachariah Tarun
General Medicine, West Suffolk Hospital, Bury St Edmunds, GBR.
Medicine, Leicester, Northamptonshire and Rutland Deanery, Leicester, GBR.
Cureus. 2023 Aug 17;15(8):e43653. doi: 10.7759/cureus.43653. eCollection 2023 Aug.
We discuss a case of a 48-year-old man who presented with symptoms of breathlessness, orthopnea, and paroxysmal nocturnal dyspnea. Echocardiogram showed severe left ventricular dysfunction with an ejection fraction of 20% and a coronary angiogram performed later was normal. He was initiated on standard medical management for heart failure. Further blood tests showed that he had severe hypocalcemia secondary to hypoparathyroidism. After the correction of hypoparathyroidism using calcium supplementation and alfacalcidol, his ejection fraction improved to 59%, and 12 weeks later, all anti-failure medications were stopped. A clinical diagnosis of hypocalcemic cardiomyopathy due to hypoparathyroidism was made. The literature review reveals only a few reported cases of heart failure as the initial presentation of dilated cardiomyopathy due to underlying hypocalcemia.
我们讨论了一例48岁男性患者,其表现为呼吸困难、端坐呼吸和阵发性夜间呼吸困难。超声心动图显示严重左心室功能障碍,射血分数为20%,随后进行的冠状动脉造影正常。他开始接受心力衰竭的标准药物治疗。进一步的血液检查显示,他因甲状旁腺功能减退继发严重低钙血症。在使用钙剂补充和阿法骨化醇纠正甲状旁腺功能减退后,他的射血分数提高到59%,12周后,所有抗心力衰竭药物均停用。作出了因甲状旁腺功能减退导致低钙性心肌病的临床诊断。文献综述显示,仅有少数报道病例以心力衰竭作为潜在低钙血症所致扩张型心肌病的首发表现。