Wen Yi, Luo Xiaolin
West China School of Nursing/West China Hospital, Sichuan University, Chengdu, China.
Department of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, China.
Front Cardiovasc Med. 2022 Sep 13;9:999550. doi: 10.3389/fcvm.2022.999550. eCollection 2022.
Hypocalcemia and its related symptoms are common manifestations in postsurgical hypoparathyroidism, but patients with hypocalcemia manifested as heart failure is rare and few cases are reported in the literature. Here we reported a 58-year-old female with hypoparathyroidism and uncontrolled hypocalcemia after thyroidectomy, presented with acute heart failure, accompanied with enlargement and reduced ejection fraction of left ventricle. She was refractory to guideline-directed medical therapy for heart failure including digitalis and diuretics. However, her symptoms resolved and cardiac function improved dramatically after normalization of serum calcium level. This rare case highlights the pivotal role of calcium in maintaining cardiac function and the importance of treating underlying reversible causes of heart failure. For patients with hypoparathyroidism, it is essential to get standard treatment to avoid development of heart failure and hypocalcemia related syndromes.
低钙血症及其相关症状是术后甲状旁腺功能减退的常见表现，但以心力衰竭为表现的低钙血症患者较为罕见，文献报道的病例较少。在此，我们报告了一名58岁女性，甲状腺切除术后出现甲状旁腺功能减退且低钙血症控制不佳，表现为急性心力衰竭，伴有左心室扩大和射血分数降低。她对包括洋地黄和利尿剂在内的心力衰竭指南指导药物治疗无效。然而，血清钙水平恢复正常后，她的症状得以缓解，心脏功能显著改善。这一罕见病例凸显了钙在维持心脏功能中的关键作用以及治疗心力衰竭潜在可逆病因的重要性。对于甲状旁腺功能减退患者，进行规范治疗以避免发生心力衰竭和低钙血症相关综合征至关重要。
