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影响过敏性鼻炎患者的常见变应原分析。

Analysis of common allergens affecting patients with allergic rhinitis.

作者信息

Ranjana Kumari, M Maheshwari

机构信息

ENT Department, Madha Medical College and Hospital, Kundrathur Main Road, Kovur, Thandalam, Tamil Nadu - 600122, India.

ENT Department, ESI Dispensary, 19, Mandapam Rd, Aspiran Garden Colony, Kilpauk, Chennai, Tamil Nadu 600010, India.

出版信息

Bioinformation. 2023 Jan 31;19(1):24-27. doi: 10.6026/97320630019024. eCollection 2023.

Abstract

Allergic rhinitis (AR) is an atopic disorder that affects the quality of life of the patients. AR symptoms include sneezing, nasal congestion, and mucus discharge. It is often associated with several other eye-, ear-, and nose-related symptoms along with fatigue and mood changes. The allergic reaction is triggered by an allergen. An understanding of the allergens that affect a patient is important for allergen avoidance, and ultimately, the treatment of AR. This study aimed to identify the common allergens affecting patients with AR. A total of 52 patients with AR were identified for this study. AR was diagnosed based on the presenting symptoms and measurement of IgE levels and absolute eosinophil counts. Skin prick tests (SPT) were performed to identify the allergen sensitivity of the patients. Patient history, family history, and a detailed account of the symptoms were recorded. Finally, correlation between family history and allergy severity was statistically evaluated. All patients presented symptoms of rhinitis with sinusitis and 61.5% of these were mild or moderate allergic. Few of the patients had ocular or otic symptoms. The duration of allergy was variable in these patients. A high proportion of patients were allergic to house dust mites (92.3%). The proportion of patients allergic to pollen, , cockroach, cotton dust, and were 84.6%, 76.9%, 75%, 65.4%, and 61.5%, respectively. Around 71.2% of patients reported a family history of allergy. SPT severity was not associated with family history (p=0.266). This study successfully identifies the common allergens affecting patients with AR from Chennai, India. It highlights the importance of SPT for the identification of allergens in deciding the treatment regimen for AR.

摘要

变应性鼻炎(AR)是一种影响患者生活质量的特应性疾病。AR症状包括打喷嚏、鼻塞和流涕。它通常还伴有其他一些与眼、耳、鼻相关的症状以及疲劳和情绪变化。过敏反应由过敏原触发。了解影响患者的过敏原对于避免接触过敏原以及最终治疗AR至关重要。本研究旨在确定影响AR患者的常见过敏原。本研究共纳入了52例AR患者。根据出现的症状以及IgE水平和嗜酸性粒细胞绝对计数的测量结果诊断AR。进行皮肤点刺试验(SPT)以确定患者的过敏原敏感性。记录患者病史、家族史以及症状的详细情况。最后,对家族史与过敏严重程度之间的相关性进行统计学评估。所有患者均表现出鼻炎伴鼻窦炎症状,其中61.5%为轻度或中度过敏。少数患者有眼部或耳部症状。这些患者的过敏持续时间各不相同。很大一部分患者对屋尘螨过敏(92.3%)。对花粉、蟑螂、棉尘等过敏的患者比例分别为84.6%、76.9%、75%、65.4%和61.5%。约71.2%的患者报告有家族过敏史。SPT严重程度与家族史无关(p = 0.266)。本研究成功确定了影响印度钦奈AR患者的常见过敏原。它突出了SPT在确定AR治疗方案时识别过敏原方面的重要性。

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