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铜配合物的生物学潜力:综述

Biological potential of copper complexes: a review.

作者信息

Ashraf Jamshaid, Riaz Muhammad Asad

机构信息

Department of Chemistry, University of Gujrat, Gujrat, Pakistan.

Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.

出版信息

Turk J Chem. 2022 Jan 4;46(3):595-623. doi: 10.55730/1300-0527.3356. eCollection 2022.

Abstract

This review comprises the inorganic compounds particularly metal coordinated complexes, as drugs play a relevant role in medicinal chemistry. It has been observed that copper complexes are potentially attractive as medicinal importance. In this review, the most remarkable achievements of copper complexes undertaken over the past few decades as antimicrobial, antioxidant, enzyme inhibition activity, and anti-cancer agents are discussed. This work was motivated by the observation that no comprehensive surveys of the diversity of biological activities of copper complexes were available in the literature.

摘要

本综述涵盖无机化合物,特别是金属配位络合物,因为这些药物在药物化学中发挥着重要作用。据观察,铜络合物因其药用价值而具有潜在吸引力。在本综述中,讨论了过去几十年来铜络合物在抗菌、抗氧化、酶抑制活性和抗癌剂方面取得的最显著成就。这项工作的动机是观察到文献中没有关于铜络合物生物活性多样性的全面调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6498/10503981/3e36ad5231ba/turkjchem-46-3-595f1.jpg

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