Almarabheh Amer, Salah Afif Ben, Alghamdi Manal, Al Saleh Aseel, Elbarbary Abdulla, Al Qashar Ahmed, Alserdieh Faisal, Alahmed Fatema, Alhaddar Hasan, Alsada Lulwa, Yosri Mohamed, Omran Mahmood, Khudhair Mina, Salih Motasem, Fuad Noora, Chlif Sadok
Department of Family and Community Medicine, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
Department of Medical Epidemiology, Pasteur Institute of Tunis, Tunis, Tunisia.
Front Psychol. 2023 Sep 1;14:1219576. doi: 10.3389/fpsyg.2023.1219576. eCollection 2023.
Limited attention is devoted to the improvement of the quality of life of patients suffering from the negative consequences of Sickle cell disease (SCD). Our study focuses on the evaluation of the performance of the WHOQOL-BREF as a tool to measure the quality of life of SCD Patients in Bahrain.
We conducted a cross-sectional study that enrolled 273 SCD patients selected using a simple random sampling technique from primary health-care centers in Bahrain in 2019. A designed questionnaire including the WHOQOL-BREF was filled by the patients in the health centers. The reliability of the WHOQOL-BREF was assessed by standardized Cronbach's alpha coefficient, and the validity was measured by convergent validity, principal component analysis and confirmatory factor analysis.
The WHOQOL-BREF had good internal consistency as Cronbach's alpha coefficient for the overall scale was 0.91. The convergent validity results indicated that the correlation coefficients values for all scale domains are significantly correlated at α < 0.01. Confirmatory factor analysis found that the four-domain structure produced a robust fit to the data.
The WHOQOL-BREF tool has high internal consistency and validity in assessing the quality of life of Sickle Disease patients in Bahrain.
对于改善镰状细胞病（SCD）负面后果患者的生活质量关注有限。我们的研究重点是评估世界卫生组织生活质量简表（WHOQOL - BREF）作为衡量巴林SCD患者生活质量工具的性能。
我们于2019年进行了一项横断面研究，通过简单随机抽样技术从巴林的初级卫生保健中心选取了273例SCD患者。患者在卫生中心填写了一份包含WHOQOL - BREF的设计问卷。通过标准化的克朗巴哈系数评估WHOQOL - BREF的信度，并通过收敛效度、主成分分析和验证性因素分析来衡量效度。
WHOQOL - BREF具有良好的内部一致性，总体量表的克朗巴哈系数为0.91。收敛效度结果表明，所有量表领域的相关系数值在α < 0.01时具有显著相关性。验证性因素分析发现，四领域结构对数据具有稳健的拟合度。
WHOQOL - BREF工具在评估巴林镰状细胞病患者生活质量方面具有较高的内部一致性和效度。
