Department of Anesthesiology and Reanimation, Medical Faculty, Ataturk University, Erzurum, Turkey.
Department of Neurosurgery, Medical Faculty, Recep Tayyip Erdogan University, Rize, Turkey.
Med Gas Res. 2024 Jan-Mar;14(1):33-37. doi: 10.4103/2045-9912.378881.
The effect of olfactory bulb lesions on the induction time of sevoflurane has never been studied. We aimed to investigate this issue. In this study, we found that the volume of olfactory bulbs and the pore of the fila olfactoria were significantly lower with the fibrosis of olfactory bulbs in animals subjected to olfactory bulbectomy. Volatile anesthetics induction times were measured in all groups. Prolonged induction was observed in olfactory bulbectomy group. It was concluded that increased induction times of sevoflurane may be due to the olfactory bulb lesion.
嗅球病变对七氟醚诱导时间的影响从未被研究过。我们旨在调查这个问题。在这项研究中，我们发现，在接受嗅球切除术的动物中，嗅球纤维化导致嗅球体积和嗅丝孔显著减小。所有组均测量挥发性麻醉剂的诱导时间。嗅球切除术组观察到诱导时间延长。结论是，七氟醚诱导时间的延长可能是由于嗅球损伤所致。
