Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan.
Division of Cardiology, Department of Internal Medicine, Nihon University Hospital, Tokyo, Japan.
Ther Hypothermia Temp Manag. 2023 Dec;13(4):230-233. doi: 10.1089/ther.2023.0041. Epub 2023 Sep 19.
A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH.
一位 50 岁男性因服用大剂量阿替洛尔、氨氯地平和艾司唑仑后出现低血压和心动过缓,被收入我院。心电图显示药物诱导性 J 波,随后发生心脏骤停。该患者经静脉-动脉体外膜肺氧合(VA-ECMO)成功抢救,亚低温治疗(TH)取得良好神经学预后。在 J 波患者中,TH 被认为会增加 J 波并导致致命性心律失常,但在本例中,VA-ECMO 快速降温使患者成功完成 TH。