Lefebvre-Vilardebo M, Boussignac G, Vieilledent C, Geschwind H, Teisseire B, Benhaiem N, Fabre M, Ladouch-Badre A
J Mal Vasc. 1986;11(3):297-302.
On the basis of two years' experience, a technique for the use of percutaneous endoluminal continuous emission Nd-YAG laser has been developed for arterial recanalisation. The effectiveness of this type of laser has been demonstrated in a large number of clots and atheromatous plaques, including calcified plaques. A balloon catheter gives a coaxial position of the fiber in center of the artery. Infusion of a blood solution containing 3 g of haemoglobin/100 ml at a rate of 20 ml/minute limits the thermal parietal lesions, improves the conditions of laser treatment and eliminates any risk of arterial perforation. No embolic debris is collected down-stream. Recanalisation of long arterial segments in amputated legs was performed prior to the human application. Ten patients have been treated with no mortality and virtually no morbidity. The narrowness of the reformed arterial lumina resulted in early re-thrombosis in the first 5 cases, requiring balloon modelling to ensure patency with a follow-up of 1 to 3 months in the 5 following patients.
基于两年的经验，已开发出一种使用经皮腔内连续发射钕钇铝石榴石激光进行动脉再通的技术。这种类型的激光在大量血栓和动脉粥样硬化斑块（包括钙化斑块）中已证明其有效性。球囊导管可使光纤在动脉中心处于同轴位置。以20毫升/分钟的速率输注含3克血红蛋白/100毫升的血液溶液可限制热壁损伤，改善激光治疗条件并消除动脉穿孔的任何风险。在下游未收集到栓塞碎片。在应用于人体之前，先对截肢腿部的长动脉段进行了再通。已治疗10例患者，无死亡病例，几乎无并发症。在前5例中，重建动脉腔的狭窄导致早期再血栓形成，需要进行球囊塑形以确保通畅，后5例患者进行了1至3个月的随访。
