Geschwind H, Boussignac G, Teisseire B, Benhaiem N, Laurent D
J Biomed Eng. 1984 Oct;6(4):281-3. doi: 10.1016/0141-5425(84)90074-8.
Nd-NAG laser carried by optical fibres 0.2 mm diameter was used in experimental studies to recanalize obstructed human cadaver arteries. Successful perforation of atheromatous plaques was obtained in all cases with a power of 12 W and a duration of exposure of 30-50 s provided that blood and not saline was used. The arterial wall was protected from injury by coaxial position of the optical fibre that was inserted into an inflated balloon catheter, and by circulating blood that cooled the system. The feasibility of guiding these devices in man was demonstrated in femoral and coronary arteries.
使用直径0.2毫米的光纤传输的钕-乙酰半胱氨酸(Nd-NAG)激光,对人体尸体阻塞动脉进行再通的实验研究。在所有病例中,只要使用血液而非生理盐水,以12瓦的功率和30 - 50秒的照射时间,均可成功穿透动脉粥样硬化斑块。通过将光纤同轴置于充气球囊导管内,并通过循环血液冷却系统,可保护动脉壁免受损伤。在股动脉和冠状动脉中证明了在人体中引导这些装置的可行性。