• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脱细胞脂肪基质作为生物支架在不同组织工程中的应用。

Application of Decellularized Adipose Matrix as a Bioscaffold in Different Tissue Engineering.

作者信息

Xiong Chenlu, Yao Wende, Tao Ran, Yang Sihan, Jiang Weiqian, Xu Yujian, Zhang Julei, Han Yan

机构信息

School of Medicine, Nankai University, Tianjin, China.

Department of Plastic and Reconstructive Surgery, The First Medical Centre, Chinese PLA General Hospital, 28 Fuxing Street, Beijing, 100853, China.

出版信息

Aesthetic Plast Surg. 2024 Mar;48(5):1045-1053. doi: 10.1007/s00266-023-03608-4. Epub 2023 Sep 19.

DOI:10.1007/s00266-023-03608-4
PMID:37726399
Abstract

With the development of tissue engineering, the application of decellularized adipose matrix as scaffold material in tissue engineering has been intensively explored due to its wide source and excellent potential in tissue regeneration. Decellularized adipose matrix is a promising candidate for adipose tissue regeneration, while modification of decellularized adipose matrix scaffold can also allow it to transcend the limitations of adipose tissue source properties and applied to other tissue engineering fields, including cartilage and bone tissue engineering, neural tissue engineering, and skin tissue engineering. In this review, we summarized the development of the applications of decellularized adipose matrix in different tissue engineering and present future perspectives.Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

随着组织工程学的发展,脱细胞脂肪基质作为组织工程中的支架材料,因其来源广泛且在组织再生方面具有优异潜力而得到了深入研究。脱细胞脂肪基质是脂肪组织再生的一个有前景的候选材料,而对脱细胞脂肪基质支架进行改性还可使其超越脂肪组织来源特性的限制,应用于其他组织工程领域,包括软骨和骨组织工程、神经组织工程以及皮肤组织工程。在本综述中,我们总结了脱细胞脂肪基质在不同组织工程中的应用进展并展望了未来前景。证据等级III 本刊要求作者为每篇文章指定一个证据等级。有关这些循证医学评级的完整描述,请参阅目录或在线作者指南www.springer.com/00266 。

相似文献

1
Application of Decellularized Adipose Matrix as a Bioscaffold in Different Tissue Engineering.脱细胞脂肪基质作为生物支架在不同组织工程中的应用。
Aesthetic Plast Surg. 2024 Mar;48(5):1045-1053. doi: 10.1007/s00266-023-03608-4. Epub 2023 Sep 19.
2
The Mechanisms of Adipose Stem Cell-Derived Exosomes Promote Wound Healing and Regeneration.脂肪干细胞衍生的外泌体促进伤口愈合和再生的机制。
Aesthetic Plast Surg. 2024 Jul;48(14):2730-2737. doi: 10.1007/s00266-024-03871-z. Epub 2024 Mar 4.
3
Effect of Injectable Acellular Adipose Matrix on Soft Tissue Reconstruction in a Murine Model.注射用去细胞脂肪基质对小鼠模型软组织重建的影响。
Aesthetic Plast Surg. 2024 Jun;48(11):2210-2219. doi: 10.1007/s00266-024-03924-3. Epub 2024 Mar 18.
4
Recent developments and clinical potential on decellularized adipose tissue.去细胞脂肪组织的最新进展和临床潜力。
J Biomed Mater Res A. 2018 Sep;106(9):2563-2574. doi: 10.1002/jbm.a.36435. Epub 2018 May 14.
5
Decellularized Adipose Tissue Scaffolds for Soft Tissue Regeneration and Adipose-Derived Stem/Stromal Cell Delivery.用于软组织再生和脂肪来源的干/基质细胞递送的脱细胞脂肪组织支架
Methods Mol Biol. 2018;1773:53-71. doi: 10.1007/978-1-4939-7799-4_6.
6
Application of decellularized bone matrix as a bioscaffold in bone tissue engineering.脱细胞骨基质作为生物支架在骨组织工程中的应用。
J Biol Eng. 2022 Jan 5;16(1):1. doi: 10.1186/s13036-021-00282-5.
7
Decellularized biological scaffold and stem cells from autologous human adipose tissue for cartilage tissue engineering.脱细胞生物支架和自体人脂肪来源干细胞用于软骨组织工程。
Methods. 2020 Jan 15;171:97-107. doi: 10.1016/j.ymeth.2019.04.020. Epub 2019 Apr 30.
8
Letter to the Editor: An Optimized Method for Adipose Stromal Vascular Fraction Isolation and its Application in Fat Grafting.给编辑的信:优化的脂肪基质血管成分分离方法及其在脂肪移植中的应用。
Aesthetic Plast Surg. 2023 Jun;47(Suppl 1):12-14. doi: 10.1007/s00266-022-02796-9. Epub 2022 Mar 2.
9
Organoids and Their Research Progress in Plastic and Reconstructive Surgery.类器官及其在整形与重建外科中的研究进展
Aesthetic Plast Surg. 2023 Apr;47(2):880-891. doi: 10.1007/s00266-022-03129-6. Epub 2022 Nov 18.
10
Application of Human Acellular Breast Dermal Matrix (ABDM) in Implant-Based Breast Reconstruction: An Experimental Study.人脱细胞乳腺真皮基质(ABDM)在乳房植入重建中的应用:一项实验研究。
Aesthetic Plast Surg. 2017 Dec;41(6):1435-1444. doi: 10.1007/s00266-017-0931-y. Epub 2017 Jul 14.

引用本文的文献

1
Decellularized Adipose Matrix Rejuvenates Photoaged Skin through Immune Microenvironment Modulation.去细胞化脂肪基质通过调节免疫微环境使光老化皮肤恢复活力。
BME Front. 2025 Aug 4;6:0166. doi: 10.34133/bmef.0166. eCollection 2025.
2
Adipose Decellularized Matrix: A Promising Skeletal Muscle Tissue Engineering Material for Volume Muscle Loss.脂肪脱细胞基质:一种用于大面积肌肉缺损的有前景的骨骼肌组织工程材料。
Biomater Res. 2025 Apr 17;29:0174. doi: 10.34133/bmr.0174. eCollection 2025.
3
Comment on: "Efficacy and Safety of Transplantation of Autologous Fat, Platelet-Rich Plasma (PRP) and Stromal Vascular Fraction (SVF) in the Treatment of Acne Scar: Systematic Review and Meta-analysis".

本文引用的文献

1
Adipogenesis or osteogenesis: destiny decision made by mechanical properties of biomaterials.脂肪生成还是骨生成:生物材料的力学性能决定命运抉择。
RSC Adv. 2022 Aug 30;12(38):24501-24510. doi: 10.1039/d2ra02841g.
2
Research Progress on the Immunogenicity and Regeneration of Acellular Adipose Matrix: A Mini Review.脱细胞脂肪基质的免疫原性与再生研究进展:一篇综述
Front Bioeng Biotechnol. 2022 Jun 6;10:881523. doi: 10.3389/fbioe.2022.881523. eCollection 2022.
3
Decellularized Human Adipose Tissue as an Alternative Graft Material for Bone Regeneration.
关于《自体脂肪、富血小板血浆(PRP)和基质血管成分(SVF)移植治疗痤疮瘢痕的疗效与安全性:系统评价与荟萃分析》的评论
Aesthetic Plast Surg. 2024 Mar;48(5):1054-1055. doi: 10.1007/s00266-023-03350-x. Epub 2023 Apr 28.
去细胞化人脂肪组织作为骨再生的替代移植物材料。
Tissue Eng Regen Med. 2022 Oct;19(5):1089-1098. doi: 10.1007/s13770-022-00451-7. Epub 2022 May 12.
4
Decellularized extracellular matrix scaffolds: Recent trends and emerging strategies in tissue engineering.去细胞化细胞外基质支架:组织工程中的最新趋势和新兴策略
Bioact Mater. 2021 Sep 23;10:15-31. doi: 10.1016/j.bioactmat.2021.09.014. eCollection 2022 Apr.
5
Methoxy polyethylene glycol modification promotes adipogenesis by inducing the production of regulatory T cells in xenogeneic acellular adipose matrix.甲氧基聚乙二醇修饰通过诱导调节性T细胞在异种脱细胞脂肪基质中的产生来促进脂肪生成。
Mater Today Bio. 2021 Nov 19;12:100161. doi: 10.1016/j.mtbio.2021.100161. eCollection 2021 Sep.
6
Membranous Extracellular Matrix-Based Scaffolds for Skin Wound Healing.用于皮肤伤口愈合的基于膜状细胞外基质的支架
Pharmaceutics. 2021 Oct 27;13(11):1796. doi: 10.3390/pharmaceutics13111796.
7
Characterized the Adipogenic Capacity of Adipose-Derived Stem Cell, Extracellular Matrix, and Microenvironment With Fat Components Grafting.通过脂肪成分移植表征脂肪来源干细胞、细胞外基质和微环境的成脂能力。
Front Cell Dev Biol. 2021 Sep 20;9:723057. doi: 10.3389/fcell.2021.723057. eCollection 2021.
8
Adipogenesis in Biomaterials Without Cell Seeds: Current Status and Perspectives.无细胞接种生物材料中的脂肪生成:现状与展望
Front Cell Dev Biol. 2021 Mar 8;9:647149. doi: 10.3389/fcell.2021.647149. eCollection 2021.
9
Tissue-Adhesive Chondroitin Sulfate Hydrogel for Cartilage Reconstruction.组织黏合剂硫酸软骨素水凝胶在软骨重建中的应用。
ACS Biomater Sci Eng. 2021 Sep 13;7(9):4230-4243. doi: 10.1021/acsbiomaterials.0c01414. Epub 2021 Feb 4.
10
Decellularized adipose tissue: A key factor in promoting fat regeneration by recruiting and inducing mesenchymal stem cells.去细胞脂肪组织:通过招募和诱导间充质干细胞促进脂肪再生的关键因素。
Biochem Biophys Res Commun. 2021 Feb 19;541:63-69. doi: 10.1016/j.bbrc.2020.12.108. Epub 2021 Jan 19.