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脱细胞脂肪基质作为生物支架在不同组织工程中的应用。

Application of Decellularized Adipose Matrix as a Bioscaffold in Different Tissue Engineering.

作者信息

Xiong Chenlu, Yao Wende, Tao Ran, Yang Sihan, Jiang Weiqian, Xu Yujian, Zhang Julei, Han Yan

机构信息

School of Medicine, Nankai University, Tianjin, China.

Department of Plastic and Reconstructive Surgery, The First Medical Centre, Chinese PLA General Hospital, 28 Fuxing Street, Beijing, 100853, China.

出版信息

Aesthetic Plast Surg. 2024 Mar;48(5):1045-1053. doi: 10.1007/s00266-023-03608-4. Epub 2023 Sep 19.

Abstract

With the development of tissue engineering, the application of decellularized adipose matrix as scaffold material in tissue engineering has been intensively explored due to its wide source and excellent potential in tissue regeneration. Decellularized adipose matrix is a promising candidate for adipose tissue regeneration, while modification of decellularized adipose matrix scaffold can also allow it to transcend the limitations of adipose tissue source properties and applied to other tissue engineering fields, including cartilage and bone tissue engineering, neural tissue engineering, and skin tissue engineering. In this review, we summarized the development of the applications of decellularized adipose matrix in different tissue engineering and present future perspectives.Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

随着组织工程学的发展,脱细胞脂肪基质作为组织工程中的支架材料,因其来源广泛且在组织再生方面具有优异潜力而得到了深入研究。脱细胞脂肪基质是脂肪组织再生的一个有前景的候选材料,而对脱细胞脂肪基质支架进行改性还可使其超越脂肪组织来源特性的限制,应用于其他组织工程领域,包括软骨和骨组织工程、神经组织工程以及皮肤组织工程。在本综述中,我们总结了脱细胞脂肪基质在不同组织工程中的应用进展并展望了未来前景。证据等级III 本刊要求作者为每篇文章指定一个证据等级。有关这些循证医学评级的完整描述,请参阅目录或在线作者指南www.springer.com/00266

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