• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

神经鞘瘤和神经纤维瘤的手术结果。

Surgical outcome of spinal schwannoma and neurofibroma.

机构信息

State University of Campinas, Campinas (SP), Brazil.

Pontifical Catholic University of Campinas, Campinas (SP), Brazil.

出版信息

Rev Assoc Med Bras (1992). 2023 Sep 18;69(9):e20230190. doi: 10.1590/1806-9282.20230190. eCollection 2023.

DOI:10.1590/1806-9282.20230190
PMID:37729358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10508894/
Abstract

OBJECTIVE

The aim of this study was to evaluate the outcome and surgical complications in patients with spinal schwannoma or neurofibroma surgically treated at the Hospital das Clínicas of the State University of Campinas.

METHODS

This was a retrospective cohort study, using medical records of patients operated between 2011 and 2021. The sample distribution was verified using the Kolmogorov-Smirnov test. The dynamics between qualitative variables were assessed using Fisher's exact test. We used means analysis to assess patient improvement based on Frankel scores.

RESULTS

A total of 16 patients were evaluated, of whom 56.25% (9) were men and 43.75% (7) were women. There were 13 (81.25%) patients with schwannomas and 3 (18.75%) with neurofibromas. Patients with deficits had neurological improvement, such as walking or with at least Frankel D or E after surgery. Laminectomy, performed in 8 patients (50%), and laminoplasty, used in 9 patients (56.25%), were the main techniques.

CONCLUSION

The surgical approach was proved to be an effective and safe alternative to the treatment of these tumors, with neurological improvement and minor surgical complications.

摘要

目的

本研究旨在评估在坎皮纳斯州立大学临床医院接受手术治疗的脊神经鞘瘤或神经纤维瘤患者的预后和手术并发症。

方法

这是一项回顾性队列研究,使用了 2011 年至 2021 年间接受手术治疗的患者的病历。样本分布通过柯尔莫哥洛夫-斯米尔诺夫检验进行验证。使用 Fisher 精确检验评估定性变量之间的动态关系。我们使用均值分析根据 Frankel 评分评估患者的改善情况。

结果

共评估了 16 名患者,其中 56.25%(9 名)为男性,43.75%(7 名)为女性。有 13 名(81.25%)患者患有神经鞘瘤,3 名(18.75%)患者患有神经纤维瘤。有神经功能缺损的患者在手术后出现了神经功能改善,例如行走能力或至少达到 Frankel D 或 E 级。椎管减压术(50%)和椎板成形术(56.25%)是主要的手术技术。

结论

手术方法被证明是治疗这些肿瘤的有效且安全的选择,可改善神经功能,且手术并发症较少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/caaff3cee2e4/1806-9282-ramb-69-09-e20230190-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/036a36356d8d/1806-9282-ramb-69-09-e20230190-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/7fd3e8917a52/1806-9282-ramb-69-09-e20230190-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/74a343eb60cd/1806-9282-ramb-69-09-e20230190-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/caaff3cee2e4/1806-9282-ramb-69-09-e20230190-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/036a36356d8d/1806-9282-ramb-69-09-e20230190-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/7fd3e8917a52/1806-9282-ramb-69-09-e20230190-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/74a343eb60cd/1806-9282-ramb-69-09-e20230190-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/833c/10508894/caaff3cee2e4/1806-9282-ramb-69-09-e20230190-gf04.jpg

相似文献

1
Surgical outcome of spinal schwannoma and neurofibroma.神经鞘瘤和神经纤维瘤的手术结果。
Rev Assoc Med Bras (1992). 2023 Sep 18;69(9):e20230190. doi: 10.1590/1806-9282.20230190. eCollection 2023.
2
Sporadic spinal schwannomas and neurofibromas - a review.散发性脊神经鞘瘤和神经纤维瘤——综述。
Folia Med (Plovdiv). 2021 Jun 30;63(3):309-314. doi: 10.3897/folmed.63.e54750.
3
Treatment of orbital schwannomas and neurofibromas.
Br J Neurosurg. 2003 Dec;17(6):541-5. doi: 10.1080/02688690310001627786.
4
Delayed outcome from surgically treated patients with benign nerve associated tumors of the extremities larger than 5 cm.手术治疗的肢体良性神经相关肿瘤大于5厘米患者的延迟预后。
Neurol Res. 2010 Jul;32(6):563-71. doi: 10.1179/016164109X12581096870113. Epub 2010 Mar 26.
5
Surgical consideration of cervical dumbbell tumors.颈椎哑铃状肿瘤的手术考量。
Acta Neurochir (Wien). 2013 Oct;155(10):1907-10. doi: 10.1007/s00701-013-1787-9. Epub 2013 Jun 5.
6
[Peripheral neurogenic tumors--surgical therapy of nerve sheath tumors. Review and personal results].
Zentralbl Chir. 1993;118(11):665-75.
7
Intradural extramedullary spinal masses treated at the Wits teaching hospitals between 2014 - 2017.2014年至2017年期间在威特沃特斯兰德大学教学医院接受治疗的硬脊膜内髓外脊髓肿块。
S Afr J Surg. 2019 Sep;57(3):58.
8
Surgical treatment of large abdominally involved primary dumbbell tumor in the lumbar region.腰椎区累及腹部的巨大原发性哑铃状肿瘤的外科治疗
J Spinal Disord Tech. 2014 Oct;27(7):E268-75. doi: 10.1097/BSD.0000000000000108.
9
High cervical spinal schwannoma; microneurosurgical management: an experience of 15 cases.高位颈椎神经鞘瘤;显微神经外科治疗:15例经验
Acta Neurol Taiwan. 2013 Jun;22(2):59-66.
10
Oculomotor Neurofibroma: A Different Histology Implying an Unsatisfying Clinical Outcome.眼肌神经纤维瘤:不同的组织学提示不满意的临床结果。
World Neurosurg. 2020 Jul;139:31-38. doi: 10.1016/j.wneu.2020.03.191. Epub 2020 Apr 11.

引用本文的文献

1
A Rare Compressive Spinal Thoracic Tumor in a Young Girl Who Presented With Rapid Progressive Lower Limb Weakness.一名年轻女孩出现快速进展的下肢无力,患有罕见的压迫性脊柱胸段肿瘤。
Cureus. 2025 Jun 16;17(6):e86117. doi: 10.7759/cureus.86117. eCollection 2025 Jun.
2
Ultrasonography diagnosis of dumbbell-shaped C5 cervical schwannoma: a case report and literature review.超声诊断哑铃形C5颈椎神经鞘瘤:病例报告及文献复习
Front Oncol. 2025 Jun 5;15:1490713. doi: 10.3389/fonc.2025.1490713. eCollection 2025.
3
[Clarification the terms and definitions related to neurofibromatosis type 1].

本文引用的文献

1
Improvement in Quality of Life Following Surgical Resection of Benign Intradural Extramedullary Tumors: A Prospective Evaluation of Patient-Reported Outcomes.良性硬脊膜外髓外肿瘤手术后生活质量的改善:患者报告结局的前瞻性评估。
Neurosurgery. 2021 Apr 15;88(5):989-995. doi: 10.1093/neuros/nyaa561.
2
Intradural Extramedullary Spinal Neoplasms: Radiologic-Pathologic Correlation.椎管内髓外肿瘤:放射-病理相关性。
Radiographics. 2019 Mar-Apr;39(2):468-490. doi: 10.1148/rg.2019180200.
3
Surgical management of intradural extramedullary tumors located anteriorly to the spinal cord.
[澄清与1型神经纤维瘤病相关的术语和定义]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2024 Oct 15;38(10):1161-1165. doi: 10.7507/1002-1892.202406088.
4
Analysis of the current status and hot topics in spinal schwannoma imaging research based on bibliometrics.基于文献计量学的脊柱神经鞘瘤影像学研究现状与热点分析
Front Neurol. 2024 Sep 10;15:1408716. doi: 10.3389/fneur.2024.1408716. eCollection 2024.
脊髓前方硬脊膜外肿瘤的手术治疗。
J Clin Neurosci. 2012 Aug;19(8):1150-3. doi: 10.1016/j.jocn.2011.08.044. Epub 2012 Jun 16.
4
Surgical management of ventral intradural spinal lesions.脊髓腹侧硬脊膜内病变的外科治疗。
J Neurosurg Spine. 2011 Jul;15(1):28-37. doi: 10.3171/2011.3.SPINE1095. Epub 2011 Apr 15.
5
Spinal cord and intradural-extraparenchymal spinal tumors: current best care practices and strategies.脊髓和硬脊膜内-实质外脊髓肿瘤:当前最佳治疗实践与策略
J Neurooncol. 2004 Aug-Sep;69(1-3):291-318. doi: 10.1023/b:neon.0000041889.71136.62.
6
Surgical strategy for cervical dumbbell tumors based on a three-dimensional classification.基于三维分类的颈椎哑铃形肿瘤手术策略
Spine (Phila Pa 1976). 2004 Jan 1;29(1):E10-4. doi: 10.1097/01.BRS.0000103662.13689.76.
7
Midline ventral intradural schwannoma of the cervical spinal cord resected via anterior corpectomy with reconstruction: technical case report and review of the literature.经前路椎体次全切除并重建术切除颈段脊髓腹侧硬膜内中线神经鞘瘤:技术病例报告及文献复习
Neurosurgery. 2003 Jun;52(6):1482-5; discussion 1485-6. doi: 10.1227/01.neu.0000065182.16584.d0.
8
Intramedullary spinal cord metastasis: report of three cases and review of the literature.脊髓髓内转移瘤:三例报告并文献复习
Surg Neurol. 1996 Oct;46(4):329-37; discussion 337-8. doi: 10.1016/s0090-3019(96)00162-0.
9
Surgical management of dumbbell tumors of the cervical spine.
Neurosurgery. 1996 Feb;38(2):294-300. doi: 10.1097/00006123-199602000-00012.