缺乏蛋白酶B的酵母突变体中的隔膜形成、细胞分裂和孢子形成。
Septum formation, cell division, and sporulation in mutants of yeast deficient in proteinase B.
作者信息
Zubenko G S, Mitchell A P, Jones E W
出版信息
Proc Natl Acad Sci U S A. 1979 May;76(5):2395-9. doi: 10.1073/pnas.76.5.2395.
Abstract
Mutants of Saccharomyces cerevisiae that carry lesions in the structural gene for proteinase B, prb1, have been isolated. Proteinase B was thought to be involved in activation of chitin synthase zymogen to allow septum formation during budding and to be involved in sporulation. The prb1 mutants are able to grow and divide and they form apparently normal septa that contain chitin. Most diploids homozygous for prb1 mutations are unable to complete sporulation.
摘要
已分离出酿酒酵母中携带蛋白酶B结构基因（prb1）损伤的突变体。蛋白酶B被认为参与几丁质合酶原的激活，以在出芽过程中形成隔膜，并参与孢子形成。prb1突变体能够生长和分裂，它们形成了明显正常的含有几丁质的隔膜。大多数prb1突变纯合的二倍体无法完成孢子形成。
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