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肝病学中的内镜检查程序:当前趋势与新进展

Endoscopic procedures in hepatology: Current trends and new developments.

作者信息

Laleman Wim, Vanderschueren Emma, Mehdi Zain Seyad, Wiest Reiner, Cardenas Andres, Trebicka Jonel

机构信息

Department of Gastroenterology and Hepatology, Section of Liver and Biliopancreatic Disorders, University Hospitals Leuven, KU LEUVEN, Leuven, Belgium; Medizinische Klinik B, Universitätsklinikum Münster, Münster University, Münster, Germany.

Department of Gastroenterology and Hepatology, Section of Liver and Biliopancreatic Disorders, University Hospitals Leuven, KU LEUVEN, Leuven, Belgium.

出版信息

J Hepatol. 2024 Jan;80(1):124-139. doi: 10.1016/j.jhep.2023.08.032. Epub 2023 Sep 18.

Abstract

Gastrointestinal endoscopy has long been a reliable backbone in the diagnosis and management of hepatobilary disorders and their complications. However, with evolving non-invasive testing, personalised medicine has reframed the utility and necessity of endoscopic screening. Conversely, the growing interest and use of endoscopic ultrasound (EUS) and advanced endoscopy within gastrointestinal units has also opened novel diagnostic and therapeutic avenues for patients with various hepatobiliary diseases. The integration of "advanced endoscopy" within the practice of hepatology is nowadays referred to as "endo-hepatology". In essence, endo-hepatology consists of two pillars: one focusing primarily on disorders of the liver parenchyma, vascular disorders, and portal hypertension, which is mainly captured via EUS, while the other targets the hepatobiliary tract via endoscopic retrograde cholangiopancreatography and advanced imaging. Applications under the umbrella of endo-hepatology include, amongst others, EUS-guided liver biopsy, EUS-guided portal pressure gradient measurement, coil and glue embolisation of gastric varices as well as cholangioscopy. As such endo-hepatology could become an attractive concept wherein advanced endoscopy might reinforce the medical management of patients with hepatobiliary disorders and their complications after initial basic work-up. In this review, we discuss current trends and future developments within endo-hepatology and the remaining hurdles to overcome.

摘要

长期以来,胃肠内镜检查一直是肝胆疾病及其并发症诊断和治疗的可靠支柱。然而,随着无创检测技术的不断发展,个性化医疗重新定义了内镜筛查的效用和必要性。相反,胃肠病科对内镜超声(EUS)和先进内镜技术的兴趣日益浓厚且应用不断增加,也为各种肝胆疾病患者开辟了新的诊断和治疗途径。如今,在肝病学实践中整合“先进内镜技术”被称为“内镜肝病学”。从本质上讲,内镜肝病学由两大支柱组成:一个主要关注肝实质疾病、血管疾病和门静脉高压,主要通过EUS来实现,而另一个则通过内镜逆行胰胆管造影术和先进成像技术针对肝胆管系统。内镜肝病学涵盖的应用包括EUS引导下肝活检、EUS引导下门静脉压力梯度测量、胃静脉曲张的线圈和胶水栓塞以及胆管镜检查等。因此,内镜肝病学可能成为一个有吸引力的概念,其中先进内镜技术可能会加强对肝胆疾病及其并发症患者在初步基础检查后的医疗管理。在这篇综述中,我们讨论了内镜肝病学的当前趋势和未来发展以及仍需克服的障碍。

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