Spigelman S S, McNeal J E, Freiha F S, Stamey T A
J Urol. 1986 Dec;136(6):1228-30. doi: 10.1016/s0022-5347(17)45292-x.
A comparison was made between tumor area estimated on rectal palpation and actual tumor size calculated from the radical prostatectomy specimen in 17 patients with prostatic carcinoma. For each patient a diagram of the rectal examination findings was superimposed onto a histological reconstruction map of the surgical specimen, and relative areas were measured with a computer. In only 1 case was there close correlation between palpated and actual tumor area. Seven patients had actual tumor areas that were more than twice the palpated area. In 5 patients the palpated areas corresponded to foci of capsular involvement, while adjacent large areas of cancer abutting the capsule were not recognized. Discrepancies of this magnitude may result not infrequently in assignment of a clinical stage B1 to tumors that are histologically stage B2.
对17例前列腺癌患者经直肠触诊估计的肿瘤面积与根据前列腺癌根治术标本计算出的实际肿瘤大小进行了比较。为每位患者将直肠检查结果图叠加到手术标本的组织学重建图上,并用计算机测量相对面积。只有1例触诊肿瘤面积与实际肿瘤面积密切相关。7例患者的实际肿瘤面积是触诊面积的两倍多。5例患者触诊的面积对应于包膜受累灶,而毗邻包膜的大片癌灶未被识别。这种程度的差异可能经常导致将组织学分期为B2期的肿瘤临床分期为B1期。