State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
Yi Chuan. 2023 Sep 20;45(9):754-764. doi: 10.16288/j.yczz.23-165.
Global climate change and population growth pose a serious threat to world food security. The current crops varieties will be insufficient to meet food needs in the future, and there is an urgent need for high yielding and quality crops varieties with strong environmental adaptability. The rapid domestication of wild species to create new germplasm that can be applied to crop breeding is a new strategy for ensuring food security. The flowering time is an important factor in determining the crop planting area and yield, and is a trait that is often selected in crop domestication. At present, the modification of flowering traits by domestication is usually achieved by direct editing of the major genes that control flowering in crop, which are very limited in number and relatively homogeneous in function. Floral transition is regulated by the complex network of environmental and endogenous signals. Here, we propose a new strategy that using genome editing to precisely modify protein function by changing protein phase separation capacity of important proteins that regulate expression of flowering genes, which may provide new options for the design of flowering traits in domestication.
全球气候变化和人口增长对世界粮食安全构成严重威胁。目前的作物品种将不足以满足未来的粮食需求，迫切需要具有高产和优质、环境适应能力强的作物品种。快速驯化野生物种以创造可应用于作物育种的新种质是确保粮食安全的新策略。开花时间是决定作物种植面积和产量的重要因素，也是作物驯化中经常选择的一个特征。目前，通过直接编辑控制作物开花的主要基因来修饰开花性状的驯化通常是通过直接编辑控制作物开花的主要基因来实现的，这些基因数量非常有限，功能相对单一。花的转变是由环境和内源性信号的复杂网络调控的。在这里，我们提出了一种新的策略，即利用基因组编辑技术通过改变调控开花基因表达的重要蛋白质的相分离能力来精确修饰蛋白质功能，这可能为驯化中开花性状的设计提供新的选择。
