Yamashiro K, Miyakawa A, Kajiwara M, Ogita M, Sasaki M, Ichikawa T
Gan No Rinsho. 1986 Sep;32(11):1395-9.
Seventy-four breast cancer patients, who had undergone outpatient excisional biopsy followed by radical mastectomy, were divided into three groups according to the types of intramammary cancer residuals: no cancer residuals--45 patients, noninvasive cancer residuals--15, and invasive cancer residuals--14. The invasive cancer residual group included nine patients with axillary metastasis and showed a significantly higher rate of five-year recurrence (8/14) than the other two groups. In some of the patients with invasive cancer residuals, the lesions were more advanced and aggressive by nature. Histopathologically, invasive cancer residuals closely correlated to the nondesmoplastic infiltrating tumor border, and noninvasive cancer residuals to intraductal cancerous spread. Most intramammary cancer residuals were found close to the wounds made by biopsy.
74例接受门诊切除活检后行根治性乳房切除术的乳腺癌患者，根据乳腺内癌残留类型分为三组：无癌残留——45例患者，非浸润性癌残留——15例，浸润性癌残留——14例。浸润性癌残留组包括9例有腋窝转移的患者，其五年复发率（8/14）显著高于其他两组。在一些有浸润性癌残留的患者中，病变本质上更晚期且侵袭性更强。组织病理学上，浸润性癌残留与非促结缔组织增生性浸润性肿瘤边界密切相关，而非浸润性癌残留与导管内癌扩散相关。大多数乳腺内癌残留位于活检伤口附近。
