Chin J Dent Res. 2023 Sep 21;26(3):179-184. doi: 10.3290/j.cjdr.b4330827.
To test the null hypothesis that dentine treatment with silver diamine fluoride (SDF), a potent antimicrobial agent, following use of proteolytic and chelating agents does not influence the wettability of an epoxy resin (AH Plus, Dentsply Sirona, Charlotte, NC, USA) and a tricalcium silicate sealer (BioRoot RCS, Septodont, Saint-Maur-des-Fossés, France).
Seventy-two intraradicular dentine specimens were divided into six groups based on the final irrigation solutions used: 2.5% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA) (NaOCl-EDTA) (group 1); NaOCl-EDTA-NaOCl (group 2); NaOCl-EDTA followed by 3.8% SDF, NaOCl-EDTA-SDF (group 3); NaOCl-EDTA-NaOCl-SDF (group 4); SDF (group 5) and saline (group 6). After irrigation, the specimens were divided into subgroups according to the sealer used, AH Plus or BioRoot RCS. Contact angles were measured using a contact angle analyser. The data were analysed using an independent t test, one-way analysis of variance (ANOVA) and Tamhane T2 post hoc test, with the level of significance set at P < 0.05.
In the epoxy resin sealer group, dentine surfaces treated with only SDF showed the lowest contact angle. This was significantly less than the groups in which NaOCl was used as the final irrigant (P < 0.05). In the tricalcium silicate-based sealer group, the groups treated with SDF showed significantly greater contact angles when compared to the control group (P < 0.05).
It was concluded that SDF conditioning of dentine favours the wettability of epoxy resin sealer but is detrimental to the wettability of tricalcium silicate sealer.
检验银胺氟化物(SDF)处理牙本质的假设,SDF 是一种有效的抗菌剂,使用蛋白水解和螯合剂后不会影响环氧树脂(AH Plus,Dentsply Sirona,Charlotte,NC,USA)和硅酸三钙密封剂(BioRoot RCS,Septodont,Saint-Maur-des-Fossés,法国)的润湿性。
根据最终冲洗液将 72 个根管内牙本质标本分为 6 组:2.5%次氯酸钠(NaOCl)和 17%乙二胺四乙酸(EDTA)(NaOCl-EDTA)(第 1 组);NaOCl-EDTA-NaOCl(第 2 组);NaOCl-EDTA 后用 3.8% SDF,NaOCl-EDTA-SDF(第 3 组);NaOCl-EDTA-NaOCl-SDF(第 4 组);SDF(第 5 组)和生理盐水(第 6 组)。冲洗后,根据使用的密封剂将标本分为 AH Plus 或 BioRoot RCS 亚组。使用接触角分析仪测量接触角。使用独立 t 检验、单因素方差分析(ANOVA)和 Tamhane T2 事后检验分析数据,显著性水平设为 P <0.05。
在环氧树脂密封剂组中,仅用 SDF 处理的牙本质表面的接触角最低。与最后冲洗液使用 NaOCl 的组相比,差异有统计学意义(P <0.05)。在硅酸三钙基密封剂组中,与对照组相比,用 SDF 处理的组的接触角显著增大(P <0.05)。
SDF 处理牙本质有利于环氧树脂密封剂的润湿性,但不利于硅酸三钙密封剂的润湿性。