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维生素A缺乏大鼠以及随后补充维生素A期间雄激素结合蛋白水平和促卵泡激素与睾丸膜的结合情况。

Androgen binding protein levels and FSH binding to testicular membranes in vitamin A deficient rats and during subsequent replenishment with vitamin A.

作者信息

Unni E, Rao M R

出版信息

J Steroid Biochem. 1986 Oct;25(4):579-83. doi: 10.1016/0022-4731(86)90406-1.

DOI:10.1016/0022-4731(86)90406-1
PMID:3773529
Abstract

ABP levels in the testes and epididymides of vitamin A deficient-retinoic acid maintained rats were only 20 and 6% respectively as compared with those in normal rats. The number of FSH receptors in the testes of vitamin A deficient rats, as measured by [125I]ovine FSH binding to isolated testicular membranes, was only 40% of that in the testes of normal rats. Supplementation of retinyl acetate to these vitamin A deficient rats for 16 days resulted in restoration of the number of FSH receptors to normal levels. On the other hand, ABP levels were restored to 32 and 34% only in the testes and epididymides respectively.

摘要

与正常大鼠相比,维生素A缺乏-视黄酸维持的大鼠睾丸和附睾中的ABP水平分别仅为20%和6%。通过[125I]羊FSH与分离的睾丸膜结合来测量,维生素A缺乏大鼠睾丸中的FSH受体数量仅为正常大鼠睾丸中的40%。给这些维生素A缺乏的大鼠补充醋酸视黄酯16天,可使FSH受体数量恢复到正常水平。另一方面,ABP水平仅在睾丸和附睾中分别恢复到32%和34%。

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