Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Faculty of Medicine and Biomedical Sciences, University of Ngaoundéré, Garoua, Cameroon.
Pulm Med. 2023 Sep 13;2023:1631802. doi: 10.1155/2023/1631802. eCollection 2023.
Little is known concerning chronic obstructive pulmonary disease (COPD) in Sub-Saharan Africa (SSA), where the disease remains underdiagnosed. We aimed to estimate its prevalence in Cameroon and look for its predictors.
Adults aged 19 years and older were randomly selected in 4 regions of Cameroon to participate in a cross-sectional community-based study. Data were collected in the participant's home or place of work. Spirometry was performed on selected participants. COPD was defined as the postbronchodilator forced expiratory volume in 1 second/forced vital capacity ratio (FEV1/FVC) < lower limit of normal, using the global lung initiative (GLI) equations for Black people. Binomial logistic regression was used to seek COPD-associated factors. The strength of the association was measured using the adjusted odds ratio (aOR).
A total of 5055 participants (median age (25-75 percentile) = 43 (30-56) years, 54.9% of women) were enrolled. COPD prevalence (95% confidence interval (95% CI)) was 2.9% (2.4, 3.3)%. Independent predictors of COPD (aOR (95% CI)) were a high educational level (4.7 (2.0, 11.1)), living in semiurban or rural locality (1.7 (1.4, 3.0)), tobacco smoking (1.7 (1.1, 2.5)), biomass fuel exposure (1.9 (1.1, 3.3)), experience of dyspnea (2.2 (1.4, 3.5)), history of tuberculosis (3.6 (1.9, 6.7)), and history of asthma (6.3 (3.4, 11.6)). Obesity was protective factor (aOR (95%CI) = 0.3 (0.2, 0.5)).
The prevalence of COPD was relatively low. Alternative risk factors such as biomass fuel exposure, history of tuberculosis, and asthma were confirmed as predictors.
在撒哈拉以南非洲（SSA），慢性阻塞性肺疾病（COPD）的知晓率较低，且该疾病的诊断仍存在不足。本研究旨在评估喀麦隆 COPD 的患病率，并寻找其预测因素。
在喀麦隆的 4 个地区，随机选择年龄在 19 岁及以上的成年人参与一项基于社区的横断面研究。数据是在参与者的家中或工作场所收集的。对选定的参与者进行了肺量测定。COPD 定义为支气管扩张剂后一秒用力呼气容积与用力肺活量的比值（FEV1/FVC）<下正常限值，使用全球肺倡议（GLI）黑人方程。二项逻辑回归用于寻找 COPD 相关因素。关联的强度用调整后的优势比（aOR）来衡量。
共纳入 5055 名参与者（中位数年龄（25-75 百分位数）= 43（30-56）岁，54.9%为女性）。COPD 的患病率（95%置信区间（95%CI））为 2.9%（2.4，3.3）%。COPD 的独立预测因素为高教育程度（4.7（2.0，11.1））、居住在半城市或农村地区（1.7（1.4，3.0））、吸烟（1.7（1.1，2.5））、生物燃料暴露（1.9（1.1，3.3））、呼吸困难史（2.2（1.4，3.5））、结核病史（3.6（1.9，6.7））和哮喘史（6.3（3.4，11.6））。肥胖是一个保护因素（aOR（95%CI）=0.3（0.2，0.5））。
COPD 的患病率相对较低。确认了其他危险因素，如生物燃料暴露、结核病史和哮喘史，作为预测因素。
