Jain Kanika, Tyagi Tarun, Hwa John
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Yale Cooperative Center of Excellence in Hematology, Yale University School of Medicine, New Haven, CT, USA.
Nat Cardiovasc Res. 2023 Sep;2(9):803-804. doi: 10.1038/s44161-023-00324-9. Epub 2023 Sep 4.
Lipid remodeling, from fatty acid transport and de novo lipid synthesis, is necessary for megakaryocyte differentiation and platelet production. Dietary saturated fatty acids, impaired fatty acid transport and/or dysfunction in lipid biogenesis can contribute to low platelet counts.
脂质重塑,从脂肪酸转运到从头合成脂质,对于巨核细胞分化和血小板生成是必需的。膳食饱和脂肪酸、脂肪酸转运受损和/或脂质生物合成功能障碍可导致血小板计数降低。