Patel Jay, Villegas Augusto
Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, USA.
Hematology and Oncology, Florida Cancer Specialists, Fleming Island, USA.
Cureus. 2023 Aug 21;15(8):e43849. doi: 10.7759/cureus.43849. eCollection 2023 Aug.
Urachal adenocarcinoma (UA) represents a rare subset of bladder tumors involving a urachal remnant. Incidental gross hematuria is often the only presenting symptom, with patients often presenting late in their course, thereby imparting an overall poor prognosis. Although there are prior case reports, there is little literature reported and no standardized treatment guidelines. We report a case of a middle-aged male who presented with incidental gross hematuria after a fall. Workup indicated the presence of a calcified bladder dome mass and pathology reported a primary urachal adenocarcinoma with pelvic nodal involvement. Patient underwent surgical resection and subsequent adjuvant, systemic chemotherapy regimen with leucovorin, fluorouracil, and oxaliplatin (FOLFOX). We hope to bring greater awareness to this rare cause of bladder malignancy.
脐尿管腺癌（UA）是膀胱肿瘤中涉及脐尿管残余的一种罕见亚型。偶然出现的肉眼血尿往往是唯一的临床表现症状，患者常在病程晚期才就诊，因此总体预后较差。尽管之前有病例报告，但相关文献报道较少，且没有标准化的治疗指南。我们报告了一例中年男性病例，该患者在跌倒后出现偶然肉眼血尿。检查发现膀胱顶部有一个钙化肿块，病理报告为原发性脐尿管腺癌伴盆腔淋巴结转移。患者接受了手术切除，随后接受了亚叶酸钙、氟尿嘧啶和奥沙利铂（FOLFOX）的辅助全身化疗方案。我们希望提高对这种罕见的膀胱恶性肿瘤病因的认识。
