Takada Tomoaki
Sumikawa Takada Dermatology Clinic Sapporo Japan.
Clin Case Rep. 2023 Sep 19;11(9):e7934. doi: 10.1002/ccr3.7934. eCollection 2023 Sep.
In reticular erythematous mucinosis, (1) the presence of dotted vessels and (2) uniform, structureless, yellowish-white spots, and patches on dermoscopy correspond to histopathological findings of (1) vessels at the tips of the dermal papillae and (2) thickening and rupture of the collagen and fiber bundles with mucin deposition, respectively.
Reticular erythematous mucinosis is a rare form of skin mucinosis that primarily affects middle-aged women, typically appearing as papules and plaques in the upper chest or midline of the back. Here, we report the case of a 75-year-old woman with skin papules and plaques left untreated for 8 years. A gross skin examination was followed by histopathological and dermoscopic examinations. The main dermoscopic findings were (1) dotted vessels and (2) uniform structureless yellowish-white spots and patches. The corresponding histopathological findings were (1) vessels at the tips of the dermal papillae and (2) thickening and rupturing of the collagen and fiber bundles with mucin deposition, respectively. Laboratory investigations revealed normal results, ruling out various autoimmune disorders. REM was diagnosed based on these findings. The study presents relevant evidence-based findings in dermatology and cutaneous pathology as it is the first description of REM using dermoscopy. Dermoscopic diagnosis without other unnecessary tests would benefit both the clinician and the patient.
在网状红斑性黏蛋白病中，（1）点状血管的存在以及（2）皮肤镜检查时均匀、无结构的黄白色斑点和斑片分别对应组织病理学表现中的（1）真皮乳头尖端的血管以及（2）伴有黏蛋白沉积的胶原和纤维束增厚及断裂。
网状红斑性黏蛋白病是一种罕见的皮肤黏蛋白病形式，主要影响中年女性，通常表现为上胸部或背部中线的丘疹和斑块。在此，我们报告一例75岁女性，其皮肤丘疹和斑块未治疗长达8年。在对皮肤进行大体检查后，进行了组织病理学和皮肤镜检查。主要的皮肤镜检查结果为（1）点状血管以及（2）均匀无结构的黄白色斑点和斑片。相应的组织病理学表现分别为（1）真皮乳头尖端的血管以及（2）伴有黏蛋白沉积的胶原和纤维束增厚及断裂。实验室检查结果正常，排除了各种自身免疫性疾病。基于这些发现诊断为网状红斑性黏蛋白病。该研究呈现了皮肤科和皮肤病理学中基于证据的相关发现，因为这是首次使用皮肤镜对网状红斑性黏蛋白病进行描述。无需其他不必要检查的皮肤镜诊断对临床医生和患者均有益。
