Department of Neurological Surgery, Vanderbilt University Medical Center, South Tower, 1215 21st Ave Suite #4200, Nashville, TN, 37232, USA.
Department of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Eur Spine J. 2023 Nov;32(11):4003-4011. doi: 10.1007/s00586-023-07920-0. Epub 2023 Sep 22.
(1) Evaluate the associations between L1-pelvic angle (L1PA) and both sagittal vertical axis (SVA) and T1-pelvic angle (T1PA), and (2) assess the clinical impact of L1PA.
A single-institution retrospective cohort study was undertaken for patients undergoing adult spinal deformity (ASD) surgery from 2013 to 2017. Ideal L1PA was defined as (0.5xPelvic Incidence)-21. Pearson correlation was performed to compare L1PA, SVA, and T1PA. Univariate/multivariate regression was performed to assess the effect of L1PA on mechanical complications, controlling for age, BMI, and postoperative pelvic incidence-lumbar lordosis mismatch (PI/LL). Due to the overlapping nature of patients with pseudarthrosis and rod fracture, these patients were analyzed together.
A total of 145 patients were included. Mean preoperative L1PA, SVA, and T1PA were 15.5 ± 8.9°, 90.7 ± 66.8 mm, and 27.1 ± 13.0°, respectively. Mean postoperative L1PA, SVA, and T1PA were 15.0 ± 8.9°, 66.7 ± 52.8 mm, and 22.3 ± 11.1°, respectively. Thirty-six (24.8%) patients achieved ideal L1PA. Though the correlation was modest, preoperative L1PA was linearly correlated with preoperative SVA (r = 0.16, r = 0.40, 95%CI = 0.22-0.60, p < 0.001) and T1PA (r = 0.41, r = 0.62, 95%CI = 0.46-0.76, p < 0.001). Postoperative L1PA was linearly correlated with postoperative SVA (r = 0.12, r = 0.37, 95%CI = 0.18-0.56, p < 0.001) and T1PA (r = 0.40, r = 0.62, 95%CI = 0.45-0.74, p < 0.001). Achieving ideal L1PA ± 5° was associated with a decreased risk of rod fracture/pseudarthrosis on univariate and multivariate regression (OR = 0.33, 95%CI = 0.12-0.86, p = 0.024). No association between achieving ideal L1PA and patient-reported outcomes was observed.
L1PA was modestly correlated with SVA and T1PA, and achieving ideal L1PA was associated with lower rates of rod fracture/pseudarthrosis. Future studies are warranted to better define the clinical implications of achieving a normal L1PA.
III.
(1)评估 L1 骨盆角(L1PA)与矢状垂直轴(SVA)和 T1 骨盆角(T1PA)之间的关联,以及(2)评估 L1PA 的临床影响。
对 2013 年至 2017 年接受成人脊柱畸形(ASD)手术的患者进行了单机构回顾性队列研究。理想的 L1PA 定义为(0.5x骨盆入射角)-21。进行 Pearson 相关性分析以比较 L1PA、SVA 和 T1PA。进行单变量/多变量回归分析以评估 L1PA 对机械并发症的影响,同时控制年龄、BMI 和术后骨盆入射角-腰椎前凸不匹配(PI/LL)。由于假关节和杆骨折患者的重叠性质,将这些患者一起进行分析。
共纳入 145 例患者。术前 L1PA、SVA 和 T1PA 的平均水平分别为 15.5±8.9°、90.7±66.8mm 和 27.1±13.0°。术后 L1PA、SVA 和 T1PA 的平均水平分别为 15.0±8.9°、66.7±52.8mm 和 22.3±11.1°。36 例(24.8%)患者达到理想的 L1PA。尽管相关性不大,但术前 L1PA 与术前 SVA(r=0.16,r=0.40,95%CI=0.22-0.60,p<0.001)和 T1PA(r=0.41,r=0.62,95%CI=0.46-0.76,p<0.001)呈线性相关。术后 L1PA 与术后 SVA(r=0.12,r=0.37,95%CI=0.18-0.56,p<0.001)和 T1PA(r=0.40,r=0.62,95%CI=0.45-0.74,p<0.001)呈线性相关。术后 L1PA 平均 ±5°与单变量和多变量回归时的杆断裂/假关节风险降低相关(OR=0.33,95%CI=0.12-0.86,p=0.024)。未观察到达到理想 L1PA 与患者报告结果之间存在关联。
L1PA 与 SVA 和 T1PA 有一定的相关性,达到理想的 L1PA 与较低的杆断裂/假关节发生率相关。需要进一步的研究来更好地定义达到正常 L1PA 的临床意义。
III。