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TBtools-II:一个“一专多能”的生物信息学大数据挖掘平台。

TBtools-II: A "one for all, all for one" bioinformatics platform for biological big-data mining.

机构信息

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Horticulture, South China Agricultural University, Guangzhou, Guangdong 510640, China; Key Laboratory of Biology and Germplasm Enhancement of Horticultural Crops in South China, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou, Guangdong 510640, China; Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou, Guangdong 510640, China.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Horticulture, South China Agricultural University, Guangzhou, Guangdong 510640, China.

出版信息

Mol Plant. 2023 Nov 6;16(11):1733-1742. doi: 10.1016/j.molp.2023.09.010. Epub 2023 Sep 22.

DOI:10.1016/j.molp.2023.09.010
PMID:37740491
Abstract

Since the official release of the stand-alone bioinformatics toolkit TBtools in 2020, its superior functionality in data analysis has been demonstrated by its widespread adoption by many thousands of users and references in more than 5000 academic articles. Now, TBtools is a commonly used tool in biological laboratories. Over the past 3 years, thanks to invaluable feedback and suggestions from numerous users, we have optimized and expanded the functionality of the toolkit, leading to the development of an upgraded version-TBtools-II. In this upgrade, we have incorporated over 100 new features, such as those for comparative genomics analysis, phylogenetic analysis, and data visualization. Meanwhile, to better meet the increasing needs of personalized data analysis, we have launched the plugin mode, which enables users to develop their own plugins and manage their selection, installation, and removal according to individual needs. To date, the plugin store has amassed over 50 plugins, with more than half of them being independently developed and contributed by TBtools users. These plugins offer a range of data analysis options including co-expression network analysis, single-cell data analysis, and bulked segregant analysis sequencing data analysis. Overall, TBtools is now transforming from a stand-alone software to a comprehensive bioinformatics platform of a vibrant and cooperative community in which users are also developers and contributors. By promoting the theme "one for all, all for one", we believe that TBtools-II will greatly benefit more biological researchers in this big-data era.

摘要

自 2020 年独立的生物信息学工具包 TBtools 正式发布以来,它在数据分析方面的卓越功能已经得到了数千名用户的广泛采用和 5000 多篇学术文章的引用的证明。现在,TBtools 已经成为生物实验室常用的工具。在过去的 3 年里,由于无数用户提供了宝贵的反馈和建议,我们对工具包的功能进行了优化和扩展,开发出了升级版本 TBtools-II。在这次升级中,我们加入了 100 多个新特性,如比较基因组分析、系统发育分析和数据可视化等。同时,为了更好地满足日益增长的个性化数据分析需求,我们推出了插件模式,允许用户根据自己的需求开发自己的插件,并管理它们的选择、安装和删除。迄今为止,插件库已经积累了 50 多个插件,其中一半以上是由 TBtools 用户独立开发和贡献的。这些插件提供了一系列数据分析选项,包括共表达网络分析、单细胞数据分析和 bulked segregant analysis 测序数据分析。总的来说,TBtools 现在正在从一个独立的软件转变为一个充满活力和合作的社区的综合生物信息学平台,在这个社区中,用户也是开发者和贡献者。通过推广“一个为全部,全部为一个”的主题,我们相信 TBtools-II 将使这个大数据时代的更多生物研究人员受益。

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