Institute of Psychology, Vilnius University, Vilnius, Lithuania.
Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.
Nurs Open. 2023 Dec;10(12):7611-7621. doi: 10.1002/nop2.2000. Epub 2023 Sep 23.
This study aimed to evaluate the relationship between psychological empowerment, depression, anxiety, and quality of life in people with haematopoietic stem cell transplantation (HSCT).
A longitudinal prospective study.
A sample of 150 people with haematological was recruited at Santaros Clinics in Lithuania between September 2020 and April 2022. Demographic characteristics, cancer-related characteristics, depression, anxiety, psychological empowerment and quality of life (QoL) were assessed using self-report questionnaires before and 10-12 weeks after HSCT. Descriptive statistics, correlation and moderation analyses were performed.
The results showed that psychological empowerment had a significant correlation with patients' depression, anxiety and QoL. Patients who were more empowered before HSCT had a subjectively better QoL before and after HSCT and were less depressed after transplantation. The results showed that empowerment was a moderator between depression and QoL after transplantation, but it had a significant effect on the QoL only among patients who are less depressed.
With this study, we aim to contribute to a better understanding of the psychological experiences of people with HSCT. Particularly, psychological empowerment is an important factor in preparing for this treatment. Medical professionals like nurses can be crucial contributors to implementing and strengthening psychological empowerment.
本研究旨在评估造血干细胞移植（HSCT）患者的心理授权、抑郁、焦虑与生活质量之间的关系。
一项纵向前瞻性研究。
2020 年 9 月至 2022 年 4 月期间，在立陶宛的 Santaros 诊所招募了 150 名血液系统疾病患者。在 HSCT 前和 10-12 周后，使用自我报告问卷评估人口统计学特征、癌症相关特征、抑郁、焦虑、心理授权和生活质量（QoL）。进行了描述性统计、相关性和调节分析。
结果表明，心理授权与患者的抑郁、焦虑和 QoL 显著相关。HSCT 前更有授权感的患者在 HSCT 前后主观上具有更好的 QoL，且移植后抑郁程度较低。结果表明，授权感是移植后抑郁与 QoL 之间的调节因素，但仅对抑郁程度较低的患者的 QoL 有显著影响。
通过这项研究，我们旨在更好地理解 HSCT 患者的心理体验。特别是，心理授权是为这种治疗做准备的一个重要因素。护士等医疗专业人员可以在实施和加强心理授权方面发挥关键作用。
