Roman-Juan Josep, Solé Ester, Sánchez-Rodríguez Elisabet, Castarlenas Elena, Jensen Mark P, Miró Jordi
Universitat Rovira i Virgili, Spain.
Department of Psychology, Unit for the Study and Treatment of Pain-ALGOS, Research Center for Behavior Assessment (CRAMC), Spain.
J Pediatr Psychol. 2023 Nov 16;48(11):931-939. doi: 10.1093/jpepsy/jsad063.
This study aimed to (1) examine the extent to which the association between exposure to adverse childhood events (ACEs) and having chronic pain in adolescents is explained by the association between exposure to ACEs and sleep disturbance and (2) explore the role of sleep disturbance in the association between exposure to ACEs and anxiety and depressive symptoms in adolescents with chronic pain.
Cross-sectional data from 469 adolescents aged 13-18 years old were drawn from an epidemiological study on pediatric chronic pain conducted in Catalonia (Spain). Participants provided self-reports of demographic characteristics, exposure to ACEs, pain characteristics, sleep disturbance, anxiety, and depressive symptoms. Mediation and moderation models were conducted.
Sleep disturbance explained a significant amount of the variance in the association between exposure to ACEs and the presence of chronic pain. Moreover, sleep disturbance explained a significant amount of the variance in the association between exposure to ACEs and depressive symptoms and moderated the association between exposure to ACEs and anxiety in adolescents with chronic pain.
The study findings suggest the possibility that addressing sleep disturbance in adolescents exposed to ACEs may help to prevent the development of chronic pain, anxiety, and depressive symptoms in those adolescents who already have chronic pain.
本研究旨在（1）探讨童年不良经历（ACEs）暴露与青少年慢性疼痛之间的关联在多大程度上可由ACEs暴露与睡眠障碍之间的关联来解释，以及（2）探究睡眠障碍在ACEs暴露与慢性疼痛青少年的焦虑和抑郁症状之间的关联中所起的作用。
来自西班牙加泰罗尼亚一项关于儿童慢性疼痛的流行病学研究的469名13 - 18岁青少年的横断面数据。参与者提供了关于人口统计学特征、ACEs暴露、疼痛特征、睡眠障碍、焦虑和抑郁症状的自我报告。进行了中介和调节模型分析。
睡眠障碍解释了ACEs暴露与慢性疼痛存在之间关联中很大一部分变异。此外，睡眠障碍解释了ACEs暴露与抑郁症状之间关联中很大一部分变异，并调节了ACEs暴露与慢性疼痛青少年焦虑之间的关联。
研究结果表明，解决ACEs暴露青少年的睡眠障碍可能有助于预防那些已经患有慢性疼痛的青少年出现慢性疼痛、焦虑和抑郁症状。
