Che W Y, Tao F B, Wu X Y
Department of Maternal, Child & Adolescent Health, School of Public Health, Anhui Medical University/MOE Key Laboratory of Population Health Across Life Cycl/Anhui Provincial Key Laboratory of Population Health＆Aristogenics, Hefei 230032, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Sep 6;57(9):1469-1474. doi: 10.3760/cma.j.cn112150-20221008-00971.
Adolescents are in a transition period from children to adults, during which they are prone to a variety of emotional disorders, with anxiety and depression being the most common disorders. Anxiety and depressive symptoms are highly correlated and the comorbidity of anxiety and depression is common. At the same time, the most prominent behavioral changes in adolescence are the emergence of getting up late and sleeping late, and the circadian rhythm begins to delay. Previous studies have shown that circadian rhythm is closely related to anxiety and depression, but the association between circadian rhythm disorder and comorbidity of anxiety and depression remains unclear. This article reviews the prevalence, association and potential biological mechanism of circadian rhythm disorder and comorbidity of anxiety and depression in adolescents, so as to provide a possible reference for the prevention and control of comorbidity of anxiety and depression in adolescents.
青少年正处于从儿童向成人的过渡阶段，在此期间他们容易出现各种情绪障碍，其中焦虑和抑郁是最常见的障碍。焦虑症状和抑郁症状高度相关，焦虑和抑郁的共病情况很常见。同时，青春期最突出的行为变化是晚睡晚起的出现，昼夜节律开始延迟。以往研究表明，昼夜节律与焦虑和抑郁密切相关，但昼夜节律紊乱与焦虑和抑郁共病之间的关联仍不明确。本文综述了青少年昼夜节律紊乱与焦虑和抑郁共病的患病率、关联性及潜在生物学机制，以期为青少年焦虑和抑郁共病的防控提供可能的参考。
