Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Japan.
Yomiuri Land Keiyu Hospital, Tokyo, Japan.
Keio J Med. 2023 Dec 25;72(4):102-105. doi: 10.2302/kjm.2022-0034-CR. Epub 2023 Sep 23.
We encountered a-27-year-old female patient who developed refractory severe headache and photophobia after the first dose of COVID-19 vaccine. Despite her prior history of migraine, we diagnosed COVID-19 vaccine-induced aseptic meningitis. Symptoms were significantly resolved after methylprednisolone therapy. On reviewing the literature, we could find only nine similar cases, with over half of them affecting women aged 20-40 years. Although uncommon, aseptic meningitis should be suspected in patients with persistent or delayed onset of headache following COVID-19 vaccination.
我们遇到了一位 27 岁的女性患者，她在接种第一剂 COVID-19 疫苗后出现难治性严重头痛和畏光。尽管她有偏头痛病史，但我们诊断为 COVID-19 疫苗引起的无菌性脑膜炎。甲基强的松龙治疗后症状明显缓解。回顾文献，我们仅发现了 9 例类似病例，其中一半以上影响 20-40 岁的女性。尽管罕见，但 COVID-19 疫苗接种后持续或延迟出现头痛的患者应怀疑无菌性脑膜炎。
