Chorzelski T P, Jablonska S, Chadzynska M, Maciejowska E, Sulej J
Pediatr Dermatol. 1986 Sep;3(4):291-4. doi: 10.1111/j.1525-1470.1986.tb00527.x.
The IgA antibody to endomysium of smooth muscle (IgA-EmA) was measured in 32 children with confirmed dermatitis herpetiformis who were eating gluten-free diets. One patient had IgA-EmA before treatment but had a negative test one month later while on the diet. Two so treated for less than one year still had antibody, but of seven children treated for more than one year with gluten-free diet, none had detectable antibody. It was present in 13 of 20 children not adhering to the prescribed diet. The antibody was absent in 4 children with linear IgA bullous dermatosis and 43 children with various skin and intestinal diseases. These findings correspond to those in adults with dermatitis herpetiformis and indicate that IgA-EmA is also a marker for gluten-sensitive enteropathy in children.
对32名确诊为疱疹样皮炎且正在食用无麸质饮食的儿童检测了平滑肌肌内膜IgA抗体（IgA-EmA）。一名患者治疗前IgA-EmA呈阳性，但在饮食治疗一个月后检测为阴性。两名接受治疗不到一年的患者仍有抗体，但在七名接受无麸质饮食治疗一年以上的儿童中，无人检测到抗体。20名未遵守规定饮食的儿童中有13名存在该抗体。4名线状IgA大疱性皮肤病患儿和43名患有各种皮肤及肠道疾病的儿童中未检测到该抗体。这些发现与成人疱疹样皮炎患者的情况相符，表明IgA-EmA也是儿童麸质敏感性肠病的一个标志物。
