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Anti-polyethylene glycol (PEG) antibody isotypes may predict PEG-associated allergy and COVID-19 protection among patients with history of suspected COVID-19 vaccine allergy.

作者信息

Kan Andy Ka Chun, Chiang Valerie, Ip Wai Ki, Au Elaine Y L, Li Philip H

机构信息

Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong.

Division of Clinical Immunology, Department of Pathology, Queen Mary Hospital, Hong Kong, Hong Kong.

出版信息

Clin Transl Allergy. 2023 Sep;13(9):e12284. doi: 10.1002/clt2.12284.

DOI:10.1002/clt2.12284
PMID:37746797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10472983/
Abstract
摘要

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Anti-polyethylene glycol (PEG) antibody isotypes may predict PEG-associated allergy and COVID-19 protection among patients with history of suspected COVID-19 vaccine allergy.抗聚乙二醇（PEG）抗体亚型可能预测疑似新冠疫苗过敏史患者的PEG相关过敏及新冠病毒感染防护情况。
Clin Transl Allergy. 2023 Sep;13(9):e12284. doi: 10.1002/clt2.12284.
2
Experience with polyethylene glycol allergy-guided risk management for COVID-19 vaccine anaphylaxis.聚乙二醇过敏导向的 COVID-19 疫苗过敏反应风险管理经验。
Allergy. 2022 Jul;77(7):2200-2210. doi: 10.1111/all.15183. Epub 2021 Dec 4.
3
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J Korean Med Sci. 2022 Aug 15;37(32):e251. doi: 10.3346/jkms.2022.37.e251.
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The Polysorbate containing AstraZeneca COVID-19 vaccine is tolerated by polyethylene glycol (PEG) allergic patients.含有聚山梨酯的阿斯利康新冠疫苗可被对聚乙二醇（PEG）过敏的患者耐受。
Clin Exp Allergy. 2022 Jan;52(1):12-17. doi: 10.1111/cea.14064. Epub 2021 Dec 9.
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Basophil reactivity to BNT162b2 is mediated by PEGylated lipid nanoparticles in patients with PEG allergy.对 PEG 过敏的患者中，对 BNT162b2 的嗜碱性粒细胞反应是由聚乙二醇化脂质纳米颗粒介导的。
J Allergy Clin Immunol. 2021 Jul;148(1):91-95. doi: 10.1016/j.jaci.2021.04.032. Epub 2021 May 12.
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[ARN COVID-19 COMIRNATY Vaccine desensitization in a case of PEG Severe Immediate Hypersensitivity].[聚乙二醇严重速发型超敏反应病例中ARN COVID-19 辉瑞疫苗脱敏治疗]
Rev Fr Allergol (2009). 2022 May;62(4):431-434. doi: 10.1016/j.reval.2021.07.007. Epub 2021 Aug 28.
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Skin Testing and Basophil Activation Testing Is Useful for Assessing Immediate Reactions to Polyethylene Glycol-Containing Vaccines.皮肤试验和嗜碱性粒细胞活化试验有助于评估对含聚乙二醇疫苗的速发型反应。
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本文引用的文献

1
COVID-19 Vaccine Allergy Safety Track (VAS-Track) pathway: real-world outcomes on vaccination rates and antibody protection.COVID-19疫苗过敏安全追踪（VAS-Track）途径：疫苗接种率和抗体保护的真实世界结果。
Asian Pac J Allergy Immunol. 2024 Dec;42(4):395-402. doi: 10.12932/AP-110722-1410.
2
Diagnostic accuracy of vaccine and vaccine excipient testing in the setting of allergic reactions to COVID-19 vaccines: A systematic review and meta-analysis.COVID-19 疫苗过敏反应疫苗和疫苗赋形剂检测的诊断准确性：系统评价和荟萃分析。
Allergy. 2023 Jan;78(1):71-83. doi: 10.1111/all.15571. Epub 2022 Nov 23.
3
Incidence of immediate allergic reactions to mRNA COVID-19 vaccines in adults with drug allergies and other allergic disorders.药物过敏和其他过敏疾病成人中对 mRNA COVID-19 疫苗的即时过敏反应发生率。
Medicine (Baltimore). 2022 Jul 29;101(30):e29571. doi: 10.1097/MD.0000000000029571.
4
Evaluation of Patients with Vaccine Allergies Prior to mRNA-Based COVID-19 Vaccination.基于mRNA的新冠疫苗接种前疫苗过敏患者的评估
Vaccines (Basel). 2022 Jun 27;10(7):1025. doi: 10.3390/vaccines10071025.
5
Anti-PEG Antibodies Boosted in Humans by SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine.SARS-CoV-2脂质纳米颗粒mRNA疫苗可增强人体中的抗聚乙二醇抗体。
ACS Nano. 2022 Aug 23;16(8):11769-11780. doi: 10.1021/acsnano.2c04543. Epub 2022 Jun 27.
6
Serum polyethylene glycol-specific IgE and IgG in patients with hypersensitivity to COVID-19 mRNA vaccines.对 COVID-19 mRNA 疫苗过敏患者的血清聚乙二醇特异性 IgE 和 IgG。
Allergol Int. 2022 Oct;71(4):512-519. doi: 10.1016/j.alit.2022.05.007. Epub 2022 Jun 6.
7
The Role of the Allergist in Coronavirus Disease 2019 Vaccine Allergy Safety: A Pilot Study on a "Hub-and-Spoke" Model for Population-Wide Allergy Service.过敏专家在 2019 冠状病毒病疫苗过敏安全中的作用：一种针对人群过敏服务的“中心辐射”模式的初步研究。
Ann Allergy Asthma Immunol. 2022 Sep;129(3):308-312.e1. doi: 10.1016/j.anai.2022.05.011. Epub 2022 May 20.
8
Experience of the first 1127 COVID-19 Vaccine Allergy Safety patients in Hong Kong - Clinical outcomes, barriers to vaccination, and urgency for reform.香港首批1127名新冠疫苗过敏安全性患者的经验——临床结果、接种障碍及改革紧迫性
World Allergy Organ J. 2022 Jan;15(1):100622. doi: 10.1016/j.waojou.2021.100622. Epub 2021 Dec 20.